PhytoHub is the first online database to inventory all phytochemicals present in foods commonly ingested with human diets. It compiles data scattered in more than 20 databases as well as data manually extracted by experts from the literature, or experimentally obtained in collaborative platforms.

It has been designed for use in nutritional metabolomics and in the field of the health effects of plant foods and their phytochemicals. Users can browse PhytoHub or make simple queries by food source, phytochemical name, molecular formula, monoisotopic mass, or MS/MS fragments, as well as more advanced queries. PhytoHub can for example list all the phytochemical precursors & metabolites matching with a monoisotopic mass found in a metabolomic profile, or list all the phytochemical metabolites expected in biological fluids after consumption of a given food.


Initial Contributors

Data Curation

A major strength of PhytoHub is its curation by scientists with expertise on the different families of phytochemicals. A web interface has been developed in 2017 to facilitate data curation. Experts can easily and very rapidly add a new information that immediately appears online.

New contributors with expertise on food phytochemicals are welcome. Please contact us if you are interested to join the project, or to give any feedback on PhytoHub to help us to improve it. Recent relevant publications can also be sent for integration by our team of curators.

Compound familyExpertsAffiliation
AlkylresorcinolsRikard LandbergSwedish University of Agricultural Sciences, Uppsala, Sweden
AnthocyaninsWieslaw WiczkowskiInstitute of Animal Reproduction and Food Research of the Polish Academy of Sciences, Olsztyn, Poland
BetalainsWieslaw WiczkowskiInstitute of Animal Reproduction and Food Research of the Polish Academy of Sciences, Olsztyn, Poland
BetalainsGesine SchmidtNofima, Department of Food and Health, As, Finland
CarotenoidsCatherine Caris-VeyratINRA Avignon, UMR408, France
CarotenoidsRachel KopecThe Ohio State University, Columbus, USA
EllagitanninsPaco Tomas-Barberan, Rocio Garcia-Villalba, Juan Carlos EspinCEBAS-CSIC, Murcia, Spain
Flavanol metabolitesPeter HollmanRIKILT Wageningen University, The Netherlands
Flavonol metabolitesClaudia Nunes dos SantosiBET, Oeiras, Portugal
Flavonol metabolitesChristine MorandINRA Clermont-Ferrand, UMR1019, France
Hydroxycinnamic acidsAndreia Bento da Silva, Maria Rosario BronzeInstitute of Chemical and Biological Technology (ITQB), Oeiras, Lisbon, Portugal
Miscellaneous phenolic acidsAndreia Bento da Silva, Maria Rosario BronzeInstitute of Chemical and Biological Technology (ITQB), Oeiras, Lisbon, Portugal
MiscellaneousMarie-Anne VernyINRA Clermont-Ferrand, UMR1019, France
MiscellaneousNatalia Vazquez-ManjarrezINRA Clermont-Ferrand, UMR1019, France
PhytoprostanesCécile GladineINRA Clermont-Ferrand, UMR1019, France
PhytosterolsLaura NyströmInstitute of Food, Nutrition and Health, ETH Zurich, Switzerland
Procyanidin metabolitesBegoña Bartolomé SualdeaInstituto de Investigación en Ciencias de la Alimentación (CIAL), CSIC-UAM, Madrid, Spain
StilbenesMireia Urpi-SardaUniversity of Barcelona, Spain
TerpenoidsYoann FillâtreEuropean Research Institute on Natural Ingredients, Grasse, France
Polyphenol metabolitesDorrain LowINRA Clermont-Ferrand, UMR1019, France

Funding

The development of PhytoHub 1.0 was supported by INRA and by the French National Agency of Research (ANR) (Project ALIA2010-007- PhenoMeNEP “Phenotyping using Metabolomics for Nutritional Epidemiology”, 2010-1013).

It is further developed in the framework of the FoodBAll project funded by the JPI Healthy Diet for Healthy Life (2014-2018). The COST Action POSITIVe is also supporting PhytoHub through generating or compiling knowledge on plant food bioactives (2014-2018).

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