Intervention Studies for the metabolite 3 β-monoglucuronyl-18-β-glycyrrhetinic acid with food phytochemical Glycyrrhizin
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Glycyrrhizin | 3 β-monoglucuronyl-18-β-glycyrrhetinic acid | Human | Urine | Host metabolism | 600 mg of glycyrrhizin dissolved in 200 ml of water (morning administration) | Pure compound | 6 | Healthy; 5M;1F; Age= 24-40 | 600 mg | single | 0.43±0.08 (SD) | 1986.97±367.33 (SD) | Publications | ||||||||
| Glycyrrhizin | 3 β-monoglucuronyl-18-β-glycyrrhetinic acid | Human | Urine | Host metabolism | 600 mg of glycyrrhizin dissolved in 200 ml of water (Evening administration) | Pure compound | 5 | Healthy;5M; Age=24-40 | 600 mg | single | 0.54±0.16 (SD) | 2501.94±743.32 (SD) | Publications |