Intervention Studies for the metabolite N-methyl-2-pyridone-5-carboxamide with food phytochemical Coffee pyrimidines
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Coffee pyrimidines | N-methyl-2-pyridone-5-carboxamide | Human | Urine | Host metabolism | 500 mL coffee | food | 10 | Healthy; 6 F, 4 M; age 22–27 y, BMI 22.6 ± 2.6 kg/m2 | 35.38 µmol | Single | 74.34 | 26.3 µmol (0-36h) | Publications |