Intervention Studies for the metabolite Sulforaphane-cysteine with food phytochemical Sulforaphane
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sulforaphane | Sulforaphane-cysteine | Human | Plasma; Urine | Host metabolism | Broccoli sprout extract | Extract | 98 | M; Age=64.9-65.7Y; BMI: 28.9-31.1 kg/m²;scheduled for prostate biopsy | 200 µmol sulforaphane | Multiple | 4-8 weeks until biopsy | 0,02±0,01 (SEM) | 1,23±0,19 (SEM) | Publications | |||||||
| Sulforaphane | Sulforaphane-cysteine | Human | Plasma; Urine | Host metabolism | Myrosinase treated broccoli sprout extract (200 µmol sulforaphane). Blood and urine samples were taken before and after the treatment. | Extract | 86 (42 with treatment and 44 without) | M; Age=65.7±5.4 y; BMI=28.9 ± 7.6 kg/m²; prostate cancer risk | 200 µmol sulforaphane/day | Multiple | 4-8 weeks | 0,02±0.01 (SEM) | 1,23±0,19 (SEM) | Publications |