Intervention Studies for the metabolite Cyanidin 3-O-glucoside with food phytochemical Cyanidin 3-O-glucoside
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cyanidin 3-O-glucoside | Cyanidin 3-O-glucoside | Human | Plasma | Unchanged | Grumixama juice | Food | 10 | 10W;Age=29.3±7.7Y;BMI=23.1±2.9Kg/m² | 10 mL/Kg bw | Single | 0.99 | 0-24h | Publications | ||||||||
| Cyanidin 3-O-glucoside | Cyanidin 3-O-glucoside | Human | Plasma | Unchanged | Grumixama juice | Food | 10 | 10W;Age=29.3±7.7Y;BMI=23.1±2.9Kg/m² | 10 mL/Kg bw | Single | 1.43 | 0-24h | Publications | ||||||||
| Cyanidin 3-O-glucoside | Cyanidin 3-O-glucoside | Human | Plasma; Urine | Unchanged | Blood orange juice | Food | 6 | Healthy;3M;3F;Age=20-24Y;Weight=58-81kg; BMI=21-31kg/m² | 1000 mL | Single | 2 | 0.2 | 0.27±0.02 µmol (SEM) (0-24h) | Publications | |||||||
| Cyanidin 3-O-glucoside | Cyanidin 3-O-glucoside | Human | Urine | Unchanged | Blackberry | Food | 5 | 2M;3F; Age=42±5Y; BMI=21± 1 kg/m² | 960 µmol | Single | 193±29 nmol (SEM) (0-24h) | Publications | |||||||||
| Cyanidin 3-O-glucoside | Cyanidin 3-O-glucoside | Human | Plasma; Urine | Unchanged | Freeze-dried black raspberries | Food | 11 | Age=29.6 ± 10.6Y; BMI=25.5±2.8 kg/m² | 45 g | Multiple | 7d | 1.09±0.3 (SEM) | 2.15±0.75 (SEM) | 6.91 | 0-12 h | 2.52±no data | Publications | ||||
| Cyanidin 3-O-glucoside | Cyanidin 3-O-glucoside | Human | Plasma; Urine | Unchanged | elderberry extract | Extract | 52 | Post-menopausal; 52F; Age=58.2 ± 5.6 y; BMI=24.7±0.6 kg/m² | 500 mg | Multiple | 1 dose per day in 12 weeks | 16 | Publications | ||||||||
| Cyanidin 3-O-glucoside | Cyanidin 3-O-glucoside | Human | Plasma | Unchanged | blueberry puree | Food | 10 | 10M;Age=20.8±1.6 y;BMI=22.5 ± 2.1 kg/m² | 348-358 mg | Single | 1.5 | 11.7±4.3 (SD) | Publications | ||||||||
| Cyanidin 3-O-glucoside | Cyanidin 3-O-glucoside | Human | Plasma; Urine | Unchanged | elderberry extract in water | Extract | 4 | Healthy;Elderly;4F;Age=67± 4Y | 720 mg | Single | 1.083±0.343 (SEM) | 42.5±4.5 (SEM) | 1.622±0.117 (SEM) | Publications | |||||||
| Cyanidin 3-O-glucoside | Cyanidin 3-O-glucoside | Human | Urine | Unchanged | Concentrated Elderberry juice | Food | 7 | 1M;6F;BMI=21.5kg/m² | 1108.2 mg | Single | 0.054±0.029 (SD) | 0.601±0.321 mg (SD) (0-5h) | Publications | ||||||||
| Cyanidin 3-O-glucoside | Cyanidin 3-O-glucoside | Human | Plasma; Urine | Unchanged | Commercial red grape juice concentrate | Food | 9 | 4M;5F;Age=24-34Y;BMI=19.7-26.3 kg/m² | 283.5 mg | Single | 0.5±0.5-0.5 (CV) | 0.42±118 (CV) | 0.6 | 0-3 h | 1.61±22.7 (CV) | 0.09 | 2.88±72.1 µg (CV) (0-7h) | Publications | |||
| Cyanidin 3-O-glucoside | Cyanidin 3-O-glucoside | Human | Plasma; Urine | Unchanged | Red wine | Food | 9 | 4M;5F;Age=24-34Y;BMI=19.7-26.3 kg/m² | 279.6 mg | Single | 0.06 | 1.45±67.3 µg (CV) (0-7h) | Publications | ||||||||
| Cyanidin 3-O-glucoside | Cyanidin 3-O-glucoside | Human | Plasma; Urine | Unchanged | Blackcurrant juice | Food | 6 | 3M;3F; Age=25.8±1.5Y; BMI=23.1± 3.2 kg/m² | 144.8 mg | Single | 1±0.5-1.5 (CV) | 0.43±42.1 (CV) | 0.22 | 0-3 h | 0.00053±31.3 (CV) | 4.19±31.3 µg (CV) (0-7h) | Publications | ||||
| Cyanidin 3-O-glucoside | Cyanidin 3-O-glucoside | Human | Plasma; Urine | Unchanged | elderberry extract | Extract | 6 | 3M;3F; Age=25.8±1.5Y; BMI=23.1± 3.2 kg/m² | 147.3 mg | Single | 1.5±1.0-2.0 (CV) | 5.02±64.9 (CV) | 9.2 | 0-3 h | 0.0025±111 (CV) | 114.1±111 µg (CV) (0-7h) | Publications | ||||
| Cyanidin 3-O-glucoside | Cyanidin 3-O-glucoside | Human | Plasma; Urine | Unchanged | Aronia extract | Extract | 6 | Healthy;6M;6F;Age=18-65Y;BMI M=25±1kg/m²; BMI F=24± 1kg/m² | 500 mg | Single | 1.6±0.24 (SEM) | 0.059±0.024 (SEM) | 0.462 | 0-24h | 0.004 | Publications | |||||
| Cyanidin 3-O-glucoside | Cyanidin 3-O-glucoside | Human | Plasma | Unchanged | strawberry beverages 10g powder | Extract | 5 | 1M;4F;BMI=42.1 ± 9.7 kg/m² | 100.9 µmol | Single | 3.8±0.5 (SD) | Publications | |||||||||
| Cyanidin 3-O-glucoside | Cyanidin 3-O-glucoside | Human | Plasma | Unchanged | strawberry beverages 20g powder | Extract | 5 | 1M;4F;BMI=42.1 ± 9.7 kg/m² | 210.3 µmol | Single | 4.5±1 (SD) | Publications | |||||||||
| Cyanidin 3-O-glucoside | Cyanidin 3-O-glucoside | Human | Plasma | Unchanged | strawberry beverages 40g powder | Extract | 5 | 1M;4F;BMI=42.1 ± 9.7 kg/m² | 368.8 µmol | Single | 6.6±2.7 (SD) | Publications | |||||||||
| Cyanidin 3-O-glucoside | Cyanidin 3-O-glucoside | Human | Plasma; Urine | Unchanged | 6,8,10,3′,5′-13C5-Cyanidin-3-glucoside | Pure compound | 8 | Healthy; 8M; Age=18-45Y; BMI=18.5-30.5kg/m² | 500 mg | Single | 1.8±0.2 (SEM) | 141±70 (SEM) | 279 | 0-48 h | 0.4 | 120±54.1 µg (SEM) (0-48h) | Publications | ||||
| Cyanidin 3-O-glucoside | Cyanidin 3-O-glucoside | Human | Plasma | Unchanged | Freeze dried WBB powder | Food | 12 | Healthy;6M;6F;Age=20-41Y;BMI=25-33kg/m² | 25 g | Single | 1.8±0 (SEM) | 2.4±0.2 (SEM) | 62.2 | 0-24h | Publications | ||||||
| Cyanidin 3-O-glucoside | Cyanidin 3-O-glucoside | Human | Plasma | Unchanged | Strawberry drink | Extract | 14 | Overweight;9M;5 premenopausalF; Age=25±4 Y, BMI= 26 ± 2kg/m² | 77 mL | Single | 2.1±0.4 (SEM) | 0.6±0.3 (SEM) | 1.7 | 0-10 h | Publications | ||||||
| Cyanidin 3-O-glucoside | Cyanidin 3-O-glucoside | Human | Plasma | Unchanged | Freeze-dried whole strawberry powder | Extract | 21 | 5M;16F; Age=39.8 ± 13.8 y; BMI=40.2± 7.2kg/m² | 10 g | Multiple | 4 days, one dose per day | 1.9±0.16 (SEM) | 4.8±0.5 (SEM) | 17.1 | 0-6 h | Publications | |||||
| Cyanidin 3-O-glucoside | Cyanidin 3-O-glucoside | Human | Plasma | Unchanged | Freeze-dried whole strawberry powder | Extract | 21 | 5M;16F; Age=39.8 ± 13.8 y; BMI=40.2± 7.2kg/m² | 20 g | Multiple | 4 days, one dose per day | 2.2±0.17 (SEM) | 6.9±0.7 (SEM) | 26 | 0-6 h | Publications | |||||
| Cyanidin 3-O-glucoside | Cyanidin 3-O-glucoside | Human | Plasma | Unchanged | Freeze-dried whole strawberry powder | Extract | 21 | 5M;16F; Age=39.8 ± 13.8 y; BMI=40.2± 7.2kg/m² | 40 g | Multiple | 4 days, one dose per day | 2.3±0.12 (SEM) | 11.3±1.3 (SEM) | 42.7 | 0-6 h | Publications |