Intervention Studies for the metabolite 17-decarboxy-neobetanin with food phytochemical Neobetanin
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Neobetanin | 17-decarboxy-neobetanin | Rat | Plasma; Urine | Unchanged | Fermented red beet juice | Food | 78 | Wistar rats; M; Weight=300 ± 15 g | 0,02 g/Kg bw | Single | 0.75 (portal vein)/0.5 (main vein) | 0.19 (portal vein); 0.29 (main vein) | 23.51 (portal vein); 16.63 (main vein) | 0-2h | 0.281 (2h) | 0.015 μmol ((0-2h)) | Publications | ||||
| Neobetanin | 17-decarboxy-neobetanin | Rat | Plasma; Urine | Unchanged | Fermented red beet juice | Food | 78 | Wistar rats; M; Weight=300 ± 15 g | 0,005 g/Kg bw | Single | 0.25 (portal and main vein) | 0.06 (portal vein); 0.02 (main vein) | 2.18 (portal vein); 1.24 (main vein) | 0-2h | 0.041 (2h) | 0.003 μmol ((0-2h)) | Publications | ||||
| Neobetanin | 17-decarboxy-neobetanin | Human | Plasma; Urine | Unknown | Fermented red beet juice | Food | 24 | Healthy; 5M; 19F;Age= 25-40 Y; BMI<30 kg/m² | 0,0007 g/Kg bw | Multiple | 6 weeks, 1 dose mornig after breakfast | after 4 week | 0,83 | 0.74 nmol (0-6 weeks) | Publications |