Intervention Studies for the metabolite Isobetanin with food phytochemical Isobetanin
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Isobetanin | Isobetanin | Human | Urine | Unchanged | Filtered liquidized beetroot | Food | 4 | Healthy;Age=18-40 | 20 mg | Single | 0.056 (6h) | 0.011 mg (0-6h) | Publications | ||||||||
| Isobetanin | Isobetanin | Human | Urine | Unchanged | Filtered liquidized beetroot | Food | 4 | Healthy;Age=18-40 | 40 mg | Single | 0.062 (6h) | 0.025 mg (0-6h) | Publications | ||||||||
| Isobetanin | Isobetanin | Human | Urine | Unchanged | Filtered liquidized beetroot | Food | 4 | Healthy;Age=18-40 | 60 mg | Single | 0.079 (6h) | 0.048 mg (0-6h) | Publications | ||||||||
| Isobetanin | Isobetanin | Human | Urine | Unchanged | Red beet juice | Food | 4 | Healthy; 2M; 2F;Age=35-55Y | 120 mg | Single | 0.5-0.9 (12h) | 0.60-1.08 mg (0-12h) | Publications | ||||||||
| Isobetanin | Isobetanin | Human | Urine | Unchanged | Red beet juice | Food | 6 | Healthy; F; Age=23-24Y; BMI=19.1-22.6 kg/m² | 363 mg | Single | Publications | ||||||||||
| Isobetanin | Isobetanin | Human | Urine | Unchanged | Red beet juice | Food | 12 | Healthy; 4M; 8F;Age= 24 ± 1 Y; BMI=25 ± 1 kg/m² | 0,0015 g/Kg bw | Single | 45.16 nmol (0-24h) | Publications | |||||||||
| Isobetanin | Isobetanin | Human | Urine | Unchanged | Red beet crunchy slices | Food | 12 | Healthy; 4M; 8F;Age= 24 ± 1 Y; BMI=25 ± 1 kg/m² | 0,0015 g/Kg bw | Single | 131.59 nmol (0-24h) | Publications | |||||||||
| Isobetanin | Isobetanin | Human | Plasma; Urine | Unchanged | Fermented red beet juice | Food | 24 | Healthy; 5M; 19F;Age= 25-40 Y; BMI<30 kg/m² | 0,0007 g/Kg bw | Multiple | 6 weeks, 1 dose mornig after breakfast | after 2 week | 11,02 | Publications | |||||||
| Isobetanin | Isobetanin | Rat | Plasma; Urine | Unchanged | Fermented red beet juice | Food | 78 | Wistar rats; M; Weight=300 ± 15 g | 0,005 g/Kg bw | Single | 0.5 (portal vein)/0.25 (main vein) | 0.30 (portal vein); 0.28 (main vein) | 2.18 (portal vein); 1.24 (main vein) | 0-2h | 1.052 (2h) | 0.076 μmol ((0-2h)) | Publications | ||||
| Isobetanin | Isobetanin | Rat | Plasma; Urine | Unchanged | Fermented red beet juice | Food | 78 | Wistar rats; M; Weight=300 ± 15 g | 0,02 g/Kg bw | Single | 0.5 (portal and main vein) | 5.93 (portal vein); 3.50 (main vein) | 23.51 (portal vein); 16.63 (main vein) | 0-2h | 18.529 (2h) | 0.806 μmol ((0-2h)) | Publications | ||||
| Isobetanin | Isobetanin | Human | Urine | Unchanged | Filtered liquidized beetroot | Food | 100 | Healthy;Age=18-40 | 60 mg | Single | 0.06-0.54 (8h) | Publications |