Intervention Studies for the metabolite Demethoxycurcumin with food phytochemical Curcuminoids
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Curcuminoids | Demethoxycurcumin | Human | Serum | Gut microbiota metabolite | bread + free curcumin (1g) | food | 10 | Healthy, age 31 ± 2 y; BMI 23.5 ± 1.2 kg/m2 | 3000 µmol | Single | 0,5 | 0,15±0,003 (SEM) | 0,22 | (0-6h) | Publications | ||||||
| Curcuminoids | Demethoxycurcumin | Human | Serum | Gut microbiota metabolite | bread + encapsulated curcumin (1g) | food | 10 | Healthy, age 31 ± 2 y; BMI 23.5 ± 1.2 kg/m2 | 3000 µmol | Single | 6 | 0,27±0,17 (SEM) | 0,75 | (0-6h) | Publications | ||||||
| Curcuminoids | Demethoxycurcumin | Human | Serum | Gut microbiota metabolite | bread + encapsulated curcumin (1g) + polyphenols | food | 10 | Healthy, age 31 ± 2 y; BMI 23.5 ± 1.2 kg/m2 | 3000 µmol | Single | 0,5 | 0,52±0,15 (SEM) | 1,38 | (0-6h) | Publications |