Intervention Studies for the metabolite 5-(4’-hydroxyphenyl)-gamma-valerolactone with food phytochemical Green tea Flavan-3-ols
Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
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Green tea Flavan-3-ols | 5-(4’-hydroxyphenyl)-gamma-valerolactone | Human | Urine | Gut microbiota metabolite | Tablets | Extract | 11 | Healthy; 9 F; 2 M; Age=28±6 y; BMI=21.8±1.6 kg/m2 | 9972 µmol | Multiple | 4 weeks (6 doses daily) | 0,1032892098 | 10.3±3,8 µmol (SEM) ((0-24h)) | Publications |