Intervention Studies for the metabolite (Epi)catechin O-sulfate with food phytochemical Red Grape pomace Flavan-3-ols
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Red Grape pomace Flavan-3-ols | (Epi)catechin O-sulfate | Human | Plasma; Urine | Host metabolism | 250 mL of red grape pomace aqueous extract | Extract | 10 | Healthy; 10 M; Age=26±2 y; BMI=27±3 kg/m2 | 983.47 µmol | Single | 1,6±0,2 (SEM) | 87±22,8 (SEM) | 166,2 | (0-24h) | 1,90±0,4 (SEM) | 0,2674204602 | 2.63±0,73 µmol (SEM) ((0-48h)) | Publications | |||
| Red Grape pomace Flavan-3-ols | (Epi)catechin O-sulfate | Human | Plasma; Urine | Host metabolism | 250 mL of red grape pomace aqueous extract | Extract | 10 | Healthy; 10 M; Age=26±2 y; BMI=27±3 kg/m2 | 983.47 µmol | Single | 2,5±0,5 (SEM) | 94,9±22,8 (SEM) | 290,2 | (0-24h) | 2,90±0,5 (SEM) | 0,2481011114 | 2.44±0,49 µmol (SEM) ((0-48h)) | Publications | |||
| Red Grape pomace Flavan-3-ols | (Epi)catechin O-sulfate | Human | Plasma; Urine | Host metabolism | 100 mL of dealcoholised red wine + grape pomace extract (1:3) | Extract | 12 | Healthy; 6 F; 6 M; Age=19-50; BMI for M=26.4±3.5 kg/m2; BMI for F=26.1±3.8 kg/m2 | 16,4 mg | Single | 92,8±23,4 (SD) | 14 | (0-24h) | 58,78318345 | 22.5±13,5 µmol (SD) ((0-24h)) | Publications | |||||
| Red Grape pomace Flavan-3-ols | (Epi)catechin O-sulfate | Human | Plasma; Urine | Host metabolism | 100 mL of dealcoholised red wine + grape pomace extract (1:3) | Extract | 12 | Healthy; 6 F; 6 M; Age=19-50; BMI for M=26.4±3.5 kg/m2; BMI for F=26.1±3.8 kg/m2 | 16,4 mg | Single | 71,2±35,8 (SD) | 16,2 | (0-24h) | 13,24581067 | 5.07±3,78 µmol (SD) ((0-24h)) | Publications | |||||
| Red Grape pomace Flavan-3-ols | (Epi)catechin O-sulfate | Human | Plasma; Urine | Host metabolism | 100 mL of dealcoholised red wine + encapsulated grape pomace extract (1:3) | Extract | 12 | Healthy; 6 F; 6 M; Age=19-50; BMI for M=26.4±3.5 kg/m2; BMI for F=26.1±3.8 kg/m2 | 16,4 mg | Single | 68±20,3 (SD) | 8,75 | (0-24h) | 84,38652558 | 32.3±13 µmol (SD) ((0-24h)) | Publications | |||||
| Red Grape pomace Flavan-3-ols | (Epi)catechin O-sulfate | Human | Plasma; Urine | Host metabolism | 100 mL of dealcoholised red wine + encapsulated grape pomace extract (1:3) | Extract | 12 | Healthy; 6 F; 6 M; Age=19-50; BMI for M=26.4±3.5 kg/m2; BMI for F=26.1±3.8 kg/m2 | 16,4 mg | Single | 64,4±22,3 (SD) | 9,93 | (0-24h) | 25,13307666 | 9.62±3,89 µmol (SD) ((0-24h)) | Publications |