Intervention Studies for the metabolite 5-(4′-Hydroxyphenyl)-γ-valerolactone-3′-glucuronide with food phytochemical Red Grape pomace Flavan-3-ols
Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
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Red Grape pomace Flavan-3-ols | 5-(4′-Hydroxyphenyl)-γ-valerolactone-3′-glucuronide | Human | Plasma; Urine | Host-gut microbiota co-metabolite | 250 mL of red grape pomace aqueous extract | Extract | 10 | Healthy; 10 M; Age=26±2 y; BMI=27±3 kg/m2 | 983.47 µmol | Single | 5,2±0,6 (SEM) | 1171,2±242,7 (SEM) | 6224,8 | (0-24h) | 12,40±8,3 (SEM) | 10,11418752 | 99.47±15,35 µmol (SEM) ((0-48h)) | Publications |