Intervention Studies for the metabolite 5-(Dihydroxyphenyl)-γ-valerolactone-sulfate with food phytochemical Green tea Flavan-3-ols
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Green tea Flavan-3-ols | 5-(Dihydroxyphenyl)-γ-valerolactone-sulfate | Human | Urine | Host-gut microbiota co-metabolite | 5 cups green tea + 50 mg vit C | Food | 50 | Healthy; Age=18-65 y; Caucasians | 1053,883432 µmol | Single | 10,437587 | 110±50 µmol (SD) ((0-24h)) | Publications | ||||||||
| Green tea Flavan-3-ols | 5-(Dihydroxyphenyl)-γ-valerolactone-sulfate | Human | Urine | Host-gut microbiota co-metabolite | 5 cups green tea + 50 mg vit C | Food | 50 | Healthy; Age=18-65 y; Caucasians | 1053,883432 µmol | Multiple | 6 weeks | 6,642100815 | 70±30 µmol (SD) ((0-24h)) | Publications | |||||||
| Green tea Flavan-3-ols | 5-(Dihydroxyphenyl)-γ-valerolactone-sulfate | Human | Urine | Host-gut microbiota co-metabolite | 5 cups green tea + 50 mg vit C | Food | 50 | Healthy; Age=18-65 y; Caucasians | 1053,883432 µmol | Multiple | 12 weeks | 4,744357725 | 50±10 µmol (SD) ((0-24h)) | Publications | |||||||
| Green tea Flavan-3-ols | 5-(Dihydroxyphenyl)-γ-valerolactone-sulfate | Human | Urine | Gut microbiota metabolite | 400 mL of green tea | Food | 20 | Healthy; Age=26±5 y; BMI=23±3 kg/m2 | 403,9 µmol | Single | 2,4 | 9.68±12,12 µmol (SD) ((0-24h)) | Publications |