Intervention Studies for the metabolite 5-(Phenyl)-γ-valerolactone-4′-sulfate with food phytochemical Cranberry Flavan-3-ols
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cranberry Flavan-3-ols | 5-(Phenyl)-γ-valerolactone-4′-sulfate | Human | Plasma | Host-gut microbiota co-metabolite | Cranberry drink | Food | 10 | Healthy; 10 M; Age=18-35 y | 375 mg | Single | 2,6±2,39 (SEM) | 0,13±0,09 (SEM) | 0,52 | (0-24h) | Publications | ||||||
| Cranberry Flavan-3-ols | 5-(Phenyl)-γ-valerolactone-4′-sulfate | Human | Plasma | Host-gut microbiota co-metabolite | Cranberry drink | Food | 10 | Healthy; 10 M; Age=18-35 y | 716 mg | Single | 2,6±2,38 (SEM) | 0,42±0,24 (SEM) | 2,7 | (0-24h) | Publications | ||||||
| Cranberry Flavan-3-ols | 5-(Phenyl)-γ-valerolactone-4′-sulfate | Human | Plasma | Host-gut microbiota co-metabolite | Cranberry drink | Food | 10 | Healthy; 10 M; Age=18-35 y | 1131 mg | Single | 2,4±2,4 (SEM) | 0,6±0,43 (SEM) | 3,39 | (0-24h) | Publications | ||||||
| Cranberry Flavan-3-ols | 5-(Phenyl)-γ-valerolactone-4′-sulfate | Human | Plasma | Host-gut microbiota co-metabolite | Cranberry drink | Food | 10 | Healthy; 10 M; Age=18-35 y | 1396 mg | Single | 2,7±2,38 (SEM) | 0,23±0,12 (SEM) | 0,94 | (0-24h) | Publications | ||||||
| Cranberry Flavan-3-ols | 5-(Phenyl)-γ-valerolactone-4′-sulfate | Human | Plasma | Host-gut microbiota co-metabolite | Cranberry drink | Food | 10 | Healthy; 10 M; Age=18-35 y | 1741 mg | Single | 3,2±2,33 (SEM) | 0,61±0,24 (SEM) | 2,48 | (0-24h) | Publications |