Intervention Studies for the metabolite 5-(4′-Hydroxyphenyl)-γ-valerolactone-3′-glucuronide with food phytochemical Cranberry Flavan-3-ols
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cranberry Flavan-3-ols | 5-(4′-Hydroxyphenyl)-γ-valerolactone-3′-glucuronide | Human | Plasma; Urine | Host-gut microbiota co-metabolite | Cranberry drink | Food | 10 | Healthy; 10 M; Age=18-35 y | 375 mg | Single | 4,7±0,67 (SEM) | 36,47±6,59 (SEM) | 309,8 | (0-24h) | 0,9687270475 | 6.21±1,47 µmol (SEM) ((0-24h)) | Publications | ||||
| Cranberry Flavan-3-ols | 5-(4′-Hydroxyphenyl)-γ-valerolactone-3′-glucuronide | Human | Plasma; Urine | Host-gut microbiota co-metabolite | Cranberry drink | Food | 10 | Healthy; 10 M; Age=18-35 y | 716 mg | Single | 4,7±0,67 (SEM) | 85,66±10,58 (SEM) | 801,06 | (0-24h) | 1,133353976 | 13.98±1,37 µmol (SEM) ((0-24h)) | Publications | ||||
| Cranberry Flavan-3-ols | 5-(4′-Hydroxyphenyl)-γ-valerolactone-3′-glucuronide | Human | Plasma; Urine | Host-gut microbiota co-metabolite | Cranberry drink | Food | 10 | Healthy; 10 M; Age=18-35 y | 1131 mg | Single | 6,2±0,47 (SEM) | 116,83±17,73 (SEM) | 1098,5 | (0-24h) | 0,8951839918 | 17.37±3,97 µmol (SEM) ((0-24h)) | Publications | ||||
| Cranberry Flavan-3-ols | 5-(4′-Hydroxyphenyl)-γ-valerolactone-3′-glucuronide | Human | Plasma; Urine | Host-gut microbiota co-metabolite | Cranberry drink | Food | 10 | Healthy; 10 M; Age=18-35 y | 1396 mg | Single | 5,8±0,36 (SEM) | 153,12±20,07 (SEM) | 1572,5 | (0-24h) | 0,9882212996 | 23.76±3,07 µmol (SEM) ((0-24h)) | Publications | ||||
| Cranberry Flavan-3-ols | 5-(4′-Hydroxyphenyl)-γ-valerolactone-3′-glucuronide | Human | Plasma; Urine | Host-gut microbiota co-metabolite | Cranberry drink | Food | 10 | Healthy; 10 M; Age=18-35 y | 1741 mg | Single | 6,4±0,5 (SEM) | 175,69±18,74 (SEM) | 1871,47 | (0-24h) | 1,01581866 | 30.41±3,24 µmol (SEM) ((0-24h)) | Publications |