Intervention Studies for the metabolite 5-(Phenyl)-γ-valerolactone-sulfate-glucuronide with food phytochemical Cranberry Flavan-3-ols
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cranberry Flavan-3-ols | 5-(Phenyl)-γ-valerolactone-sulfate-glucuronide | Human | Plasma; Urine | Host-gut microbiota co-metabolite | Cranberry drink | Food | 10 | Healthy; 10 M; Age=18-35 y | 375 mg | Single | 6,28±4,74 (SEM) | 12,16 | (0-24h) | 0,2870302363 | 1.84±0,49 µmol (SEM) ((0-24h)) | Publications | |||||
| Cranberry Flavan-3-ols | 5-(Phenyl)-γ-valerolactone-sulfate-glucuronide | Human | Plasma; Urine | Host-gut microbiota co-metabolite | Cranberry drink | Food | 10 | Healthy; 10 M; Age=18-35 y | 716 mg | Single | 2,2±0,92 (SEM) | 2,23±1 (SEM) | 5,72 | (0-24h) | 0,2732047854 | 3.37±0,53 µmol (SEM) ((0-24h)) | Publications | ||||
| Cranberry Flavan-3-ols | 5-(Phenyl)-γ-valerolactone-sulfate-glucuronide | Human | Plasma; Urine | Host-gut microbiota co-metabolite | Cranberry drink | Food | 10 | Healthy; 10 M; Age=18-35 y | 1131 mg | Single | 4,2±2,39 (SEM) | 2,67±1,13 (SEM) | 22,36 | (0-24h) | 0,2092370182 | 4.06±1,42 µmol (SEM) ((0-24h)) | Publications | ||||
| Cranberry Flavan-3-ols | 5-(Phenyl)-γ-valerolactone-sulfate-glucuronide | Human | Plasma; Urine | Host-gut microbiota co-metabolite | Cranberry drink | Food | 10 | Healthy; 10 M; Age=18-35 y | 1396 mg | Single | 3,3±1,14 (SEM) | 3,93±1,32 (SEM) | 30,09 | (0-24h) | 0,2033839291 | 4.89±0,99 µmol (SEM) ((0-24h)) | Publications | ||||
| Cranberry Flavan-3-ols | 5-(Phenyl)-γ-valerolactone-sulfate-glucuronide | Human | Plasma; Urine | Host-gut microbiota co-metabolite | Cranberry drink | Food | 10 | Healthy; 10 M; Age=18-35 y | 1741 mg | Single | 2,8±0,95 (SEM) | 3,53±1,54 (SEM) | 24,69 | (0-24h) | 0,2057692518 | 6.16±1,11 µmol (SEM) ((0-24h)) | Publications |