Intervention Studies for the metabolite Procyanidin dimer B2 with food phytochemical Procyanidin dimer B2
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Procyanidin dimer B2 | Procyanidin dimer B2 | Human | Urine | Unchanged | 99 g of nut cream (20 % of cocoa) | Food | 12 | Healthy; 4 M; 8 F; Age=24±3; BMI=23.1±1.5 kg/m2 | 190 µmol | Multiple | 1 dose morning + 1 dose at lunch + 1 dose at dinner | 0,0008210526316 | 1.56 nmol ((0-24h)) | Publications | |||||||
| Procyanidin dimer B2 | Procyanidin dimer B2 | Human | Urine | Unchanged | 99 g of cocoa-nut cream + cocoa in free form | Food | 12 | Healthy; 4 M; 8 F; Age=24±3; BMI=23.1±1.5 kg/m2 | 385,1 µmol | Multiple | 1 dose morning + 1 dose at lunch + 1 dose at dinner | 0,0006959231368 | 2.68 nmol ((0-24h)) | Publications | |||||||
| Procyanidin dimer B2 | Procyanidin dimer B2 | Human | Urine | Unchanged | 99 g of cocoa-nut cream + cocoa in encapsulated form | Food | 12 | Healthy; 4 M; 8 F; Age=24±3; BMI=23.1±1.5 kg/m2 | 385,3 µmol | Multiple | 1 dose morning + 1 dose at lunch + 1 dose at dinner | 0,0007085388009 | 2.73±1,8 µmol (SEM) ((0-24h)) | Publications |