Intervention Studies for the metabolite (−)-Epicatechin-7-sulfate with food phytochemical (-)-Epicatechin
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| (-)-Epicatechin | (−)-Epicatechin-7-sulfate | Human | Plasma | Host metabolism | cocoa dairy-based drink | Food | 10 | Healthy; Age=32±1 y; BMI=24±2 kg/m2 | 1100 mg | Single | 2 | 12±1 (SEM) | Publications | ||||||||
| (-)-Epicatechin | (−)-Epicatechin-7-sulfate | Human | plasma | Host metabolism | 50 mL of solution + 60 mg of 14C-Epicatechin | Pure compound | 8 | Healthy; 8 M; Age=31±3; BMI=24.5±3.3 kg/m2 | 207 µmol | Single | 1,1±0,2 (SEM) | 19±3 (SEM) | 43 | (0-24h) | 2,20±0,4 (SEM) | Publications |