Intervention Studies for the metabolite 5-(4'-hydroxyphenyl)-gamma-valerolactone-3'-sulfate with food phytochemical Black tea Flavan-3-ols
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Black tea Flavan-3-ols | 5-(4'-hydroxyphenyl)-gamma-valerolactone-3'-sulfate | Human | Plasma | Host-gut microbiota co-metabolite | 1 capsule of black tea (2650 mg) + 250 mL water | Extract | 6 | Healthy; Age=19-65 y; BMI=18.6-24.2 kg/m2 | 111,3 mg | Single | 5 | 0,034 | 198 | (0-30h) | Publications | ||||||
| Black tea Flavan-3-ols | 5-(4'-hydroxyphenyl)-gamma-valerolactone-3'-sulfate | Human | Urine | Host-gut microbiota co-metabolite | acqueous extract of 1 g black tea leaves | Food | 2 | Healthy; 2 M; Age=31.0±2.8 y; BMI=26.0±3.0 kg/m2 | 1014 µmol | Single | 0,01558185404 | 158±113 nmol (SEM) ((0-30h)) | Publications |