Intervention Studies for the metabolite 5-(Phenyl)-γ-valerolactone-3′-glucuronide with food phytochemical Black tea Flavan-3-ols
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Black tea Flavan-3-ols | 5-(Phenyl)-γ-valerolactone-3′-glucuronide | Human | Plasma | Host-gut microbiota co-metabolite | 1 capsule of black tea (2650 mg) + 250 mL water | Extract | 6 | Healthy; Age=19-65 y; BMI=18.6-24.2 kg/m2 | 111,3 mg | Single | 8 | 0,001 | 4 | (0-30h) | Publications |