Intervention Studies for the metabolite (+)-Epicatechin-glucuronide with food phytochemical (+)-Epicatechin
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| (+)-Epicatechin | (+)-Epicatechin-glucuronide | Human | Plasma | Host metabolism | Encapsulated (+)-Epicatechin | Pure compound | 4 | Healthy; 3 M; 1 F. Age=46±9 y. BMI=33.9±2.7 kg/m2 | 10 mg | Single | 1±(0.5-2.0) (IR) | 0,9±0,42 (SEM) | 1,5 | (0-24h) | Publications | ||||||
| (+)-Epicatechin | (+)-Epicatechin-glucuronide | Human | Plasma | Host metabolism | Encapsulated (+)-Epicatechin | Pure compound | 4 | Healthy; 2 M; 2 F; Age=60±2 y. BMI=32.1±2.2 kg/m2 | 30 mg | Single | 1±1 (IR) | 10,3±4,6 (SEM) | 22 | (0-24h) | 2,30±0,5 (SEM) | Publications | |||||
| (+)-Epicatechin | (+)-Epicatechin-glucuronide | Human | Plasma | Host metabolism | Encapsulated (+)-Epicatechin | Pure compound | 4 | Healthy; 3 M; 1 F; Age=68±1 y; BMI=31.6±1.3 kg/m2 | 100 mg | Single | 1±(1-2) (IR) | 52,4±24,1 (SEM) | 185,8 | (0-24h) | 2,60±0,2 (SEM) | Publications |