Intervention Studies for the metabolite Methoxy-(epi)catechin-glucuronide with food phytochemical Red Grape pomace Flavan-3-ols
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Red Grape pomace Flavan-3-ols | Methoxy-(epi)catechin-glucuronide | Human | Plasma; Urine | Host metabolism | 100 mL of dealcoholised red wine + grape pomace extract (1:3) | Extract | 12 | Healthy; 6 F; 6 M; Age=19-50; BMI for M=26.4±3.5 kg/m2; BMI for F=26.1±3.8 kg/m2 | 16,4 mg | Single | 22,9±20,5 (SD) | 3,92 | (0-24h) | 3,317984133 | 1.27±0,87 µmol (SD) ((0-24h)) | Publications | |||||
| Red Grape pomace Flavan-3-ols | Methoxy-(epi)catechin-glucuronide | Human | Plasma; Urine | Host metabolism | 100 mL of dealcoholised red wine + grape pomace extract (1:3) | Extract | 12 | Healthy; 6 F; 6 M; Age=19-50; BMI for M=26.4±3.5 kg/m2; BMI for F=26.1±3.8 kg/m2 | 16,4 mg | Single | 16,7±1,5 (SD) | 2,27 | (0-24h) | 4,101759912 | 1.57±1 µmol (SD) ((0-24h)) | Publications | |||||
| Red Grape pomace Flavan-3-ols | Methoxy-(epi)catechin-glucuronide | Human | Plasma; Urine | Host metabolism | 100 mL of dealcoholised red wine + encapsulated grape pomace extract (1:3) | Extract | 12 | Healthy; 6 F; 6 M; Age=19-50; BMI for M=26.4±3.5 kg/m2; BMI for F=26.1±3.8 kg/m2 | 16,4 mg | Single | 24,4±22,1 (SD) | 3,84 | (0-24h) | 4,336892646 | 1.66±1,15 µmol (SD) ((0-24h)) | Publications | |||||
| Red Grape pomace Flavan-3-ols | Methoxy-(epi)catechin-glucuronide | Human | Plasma; Urine | Host metabolism | 100 mL of dealcoholised red wine + encapsulated grape pomace extract (1:3) | Extract | 12 | Healthy; 6 F; 6 M; Age=19-50; BMI for M=26.4±3.5 kg/m2; BMI for F=26.1±3.8 kg/m2 | 16,4 mg | Single | 23,3±18,7 (SD) | 1,97 | (0-24h) | 7,393618185 | 2.83±2,26 µmol (SD) ((0-24h)) | Publications |