Intervention Studies for the metabolite 5-(4′-Hydroxyphenyl)-γ-valerolactone-3′-glucuronide with food phytochemical (-)-Epicatechin
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| (-)-Epicatechin | 5-(4′-Hydroxyphenyl)-γ-valerolactone-3′-glucuronide | Human | Plasma; Urine | Host-gut microbiota co-metabolite | 50 mL of solution + 60 mg of 14C-Epicatechin | Pure compound | 8 | Healthy; 8 M; Age=31±3; BMI=24.5±3.3 kg/m2 | 207 µmol | Single | 6,8±0,8 (SEM) | 125±30 (SEM) | 1908 | (0-24h) | 3,10±0,6 (SEM) | 6,763285024 | 14.0±2 µmol (SEM) ((0-48h)) | Publications |