Intervention Studies for the metabolite 5-(3'-hydroxyphenyl)-γ-valerolactone-4'-sulfate with food phytochemical Cranberry Flavan-3-ols
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cranberry Flavan-3-ols | 5-(3'-hydroxyphenyl)-γ-valerolactone-4'-sulfate | Human | Urine | Host-gut microbiota co-metabolite | 450 mL of cranberry drink | Food | 10 | Healthy; 10 M; Age=18-35 y | 716 mg | Single | 0,8889289233 | 10965±2757 nmol (SEM) ((0-24h)) | Publications | ||||||||
| Cranberry Flavan-3-ols | 5-(3'-hydroxyphenyl)-γ-valerolactone-4'-sulfate | Human | Plasma | Host-gut microbiota co-metabolite | 450 mL of cranberry drink | Food | 10 | Healthy; Age=18-35 y | 375 mg | Single | 4,3±0,8 (SEM) | 189±80 (SEM) | 1577 | (0-24h) | Publications | ||||||
| Cranberry Flavan-3-ols | 5-(3'-hydroxyphenyl)-γ-valerolactone-4'-sulfate | Human | Plasma | Host-gut microbiota co-metabolite | 450 mL of cranberry drink | Food | 10 | Healthy; Age=18-35 y | 716 mg | Single | 3,1±0,6 (SEM) | 306±60 (SEM) | 2582 | (0-24h) | Publications | ||||||
| Cranberry Flavan-3-ols | 5-(3'-hydroxyphenyl)-γ-valerolactone-4'-sulfate | Human | Plasma | Host-gut microbiota co-metabolite | 450 mL of cranberry drink | Food | 10 | Healthy; Age=18-35 y | 1131 mg | Single | 6,7±2,3 (SEM) | 303±53 (SEM) | 3398 | (0-24h) | Publications | ||||||
| Cranberry Flavan-3-ols | 5-(3'-hydroxyphenyl)-γ-valerolactone-4'-sulfate | Human | Plasma | Host-gut microbiota co-metabolite | 450 mL of cranberry drink | Food | 10 | Healthy; Age=18-35 y | 1396 mg | Single | 6±2,3 (SEM) | 430±111 (SEM) | 4098 | (0-24h) | Publications | ||||||
| Cranberry Flavan-3-ols | 5-(3'-hydroxyphenyl)-γ-valerolactone-4'-sulfate | Human | Plasma | Host-gut microbiota co-metabolite | 450 mL of cranberry drink | Food | 10 | Healthy; Age=18-35 y | 1741 mg | Single | 6,2±2,3 (SEM) | 683±203 (SEM) | 5614 | (0-24h) | Publications |