Intervention Studies for the metabolite Sulforaphane-glutathione with food phytochemical Glucoraphanin

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	Food Phytochemical		Metabolite	Species	Biofluids	Origin	Dietary Source Description	Dietary Source Classification	Total Number of Subjects	Description of Population	Ingested Amount	Single/Multiple Dose	Duration of the Study	Tmax (h)	Cmax (nM)	AUC (nM/h)	Time covered by AUC (h)	t 1/2 (h)	% of 24h Urinary Excretion	Excreted Amount & Time Interval	Publications

	Food Phytochemical		Metabolite	Species	Biofluids	Origin	Dietary Source Description	Dietary Source Classification	Total Number of Subjects	Description of Population	Ingested Amount	Single/Multiple Dose	Duration of the Study	Tmax (h)	Cmax (nM)	AUC (nM/h)	Time covered by AUC (h)	t 1/2 (h)	% of 24h Urinary Excretion	Excreted Amount & Time Interval	Publications
	Glucoraphanin		Sulforaphane-glutathione	Human	Urine	Host metabolism	Broccoli sprouts (20 g) containing 64 µmol of glucoraphanin	Food	14	Healthy women; age= 27-36 Y	Broccoli sprouts (20 g) containing 64 µmol of glucoraphanin	Multiple	7 days								Publications
	Glucoraphanin		Sulforaphane-glutathione	Human	Plasma; Urine	Host metabolism	Broccoli (200g) with 20 g of raw daikon radish	Food	18	Healthy; 8M; 10W; Age=37–65 years; BMI = 19-37 kg/m²	200 g	Multiple	17 days once a day	1-3							Publications
	Glucoraphanin		Sulforaphane-glutathione	Human	Plasma; Urine	Host metabolism	200 g of uncooked broccoli florets	Food	6	Healthy; Age=28-67 Y; BMI= 25.3-28.1Kg/m²	200 g uncooked broccoli florets	Single									Publications
	Glucoraphanin		Sulforaphane-glutathione	Human	Plasma	Host metabolism	Myrosinase-activated broccoli seed extract (BroccoMax®). Blood samples were taken at 0, 0.5, 1, 2, 4 and 8 hours.	Extract	6	Healthy; F; Age= 18-35Y	32 mg sulforaphane	Single		2 (SEM)	280	845,7	0-8h				Publications
	Glucoraphanin		Sulforaphane-glutathione	Human	Plasma	Host metabolism	Myrosinase-non activated broccoli seed extract (BroccoMax®). Blood samples were taken at 0, 0.5, 1, 2, 4 and 8 hours.	Extract	6	Healthy; F; Age= 18-35Y	32 mg sulforaphane	Single		0.5 (SEM)	140	443,9	0-8h				Publications
	Glucoraphanin		Sulforaphane-glutathione	Human	Plasma; Urine	Host metabolism	200 g of blanched and frozen broccoli (100g in breakfast and 100g in the dinner) ( 147.6μmol ofglucoraphanin and 3.6μmol of glucoerucin).	Food	18	Healthy;9M;8F;Age=40-70Y	200g (the day before the study treated group eat only 100g and the day of the study all volunteers treated and non-treated eat 200g)	Multiple	17 days			6	24h		0		Publications

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