Intervention Studies for the metabolite Benzyl isothiocyanate-N-acetylcysteine with food phytochemical Glucotropaeolin
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Glucotropaeolin | Benzyl isothiocyanate-N-acetylcysteine | Human | Plasma; Urine | Host metabolism | 1.71 µmol of Benzyl-GLS and 191 µmol of BITC. | Extract | 4 | Healthy; 4 W; age= 26-61Y; BMI= 19-28 Kg/m² | 1.71 µmol of Benzyl-GLS and 191 µmol of BITC | Single | 1-48 h | 3 | 60 µmol (0-48h) | Publications | |||||||
| Glucotropaeolin | Benzyl isothiocyanate-N-acetylcysteine | Human | Plasma; Urine | Host metabolism | Single dose of bread (100 g) enriched with nasturtium leaves (4.3 µmol of Benzyl-GLS and 2.48 µmol of BITC) | Extract | 4 | Healthy; 4 W; age= 26-61Y; BMI= 19-28 Kg/m² | 4.3 µmol of Benzyl-GLS and 2.48 µmol of BITC | Single | 1-48 h | 3 | 10 - (0-48h) | Publications |