Intervention Studies for the metabolite Caffeic acid with food phytochemical Tomato (Poly)phenols
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Tomato (Poly)phenols | Caffeic acid | Human | Urine | Gut microbiota metabolite | 100g of tomato sauce without oil | food | 5 | Healthy; M; Age=25-36 y; BMI=25±1.2 kg/m2 | 2048,85 µmol | Single | 0,01 | 121.8nmol(0-24h)±41,2 (SEM) (121.8nmol(0-24h)) | Publications | ||||||||
| Tomato (Poly)phenols | Caffeic acid | Human | Urine | Gut microbiota metabolite | 100g of tomato sauce with 5% virgin olive oil | food | 5 | Healthy; M; Age=25-36 y; BMI=25±1.2 kg/m2 | 1664,71 µmol | Single | 0,01 | 231.1nmol(0-24h)±130,9 (SEM) (231.1nmol(0-24h)) | Publications | ||||||||
| Tomato (Poly)phenols | Caffeic acid | Human | Urine | Gut microbiota metabolite | 100g of tomato sauce with 5% refined oil | food | 5 | Healthy; M; Age=25-36 y; BMI=25±1.2 kg/m2 | 1694,84 µmol | Single | 0,01 | 101.3nmol(0-24h)±46,9 (SEM) (101.3nmol(0-24h)) | Publications | ||||||||
| Tomato (Poly)phenols | Caffeic acid | Human | Urine | Gut microbiota metabolite | 500 g of raw tomatoes | food | 8 | Healthy; 4 F; Age=27-46 y; BMI= 23 ± 0.93 kg/m2 | 14,15 µmol | Single | 2,68 | 0.38µmol(0-24h) (0.38µmol(0-24h)) | Publications | ||||||||
| Tomato (Poly)phenols | Caffeic acid | Human | Urine | Gut microbiota metabolite | 250 g of raw tomato sauce | food | 8 | Healthy; 4 F; Age=27-46 y; BMI= 23 ± 0.93 kg/m2 | 19,18 µmol | Single | 0,75 | 0.14µmol(0-24h) (0.14µmol(0-24h)) | Publications | ||||||||
| Tomato (Poly)phenols | Caffeic acid | Human | Urine | Gut microbiota metabolite | 250 g of refined olive oil-enriched tomato sauce | food | 8 | Healthy; 4 F; Age=27-46 y; BMI= 23 ± 0.93 kg/m2 | 20,06 µmol | Single | 0,98 | 0.19µmol(0-24h) (0.19µmol(0-24h)) | Publications | ||||||||
| Tomato (Poly)phenols | Caffeic acid | Human | Urine | Gut microbiota metabolite | 500 g of tomato | food | 40 | Healthy; 19 M; 21 F; Age=28±11 y; BMI=23.3±3.8 Kg/m2 | 20,38 µmol | Single | 13,74 | 2.8µmol (0-24 (SD) (h)) | Publications | ||||||||
| Tomato (Poly)phenols | Caffeic acid | Human | Urine | Gut microbiota metabolite | 250 g of tomato sauce | food | 40 | Healthy; 19 M; 21 F; Age=28±11 y; BMI=23.3±3.8 Kg/m2 | 22,92 µmol | Single | 10,91 | 2.5µmol(0-24h) (2.5µmol(0-24h)) | Publications | ||||||||
| Tomato (Poly)phenols | Caffeic acid | Human | Urine | Gut microbiota metabolite | 250 g of tomato sauce + refined olive oil (5%) | food | 40 | Healthy; 19 M; 21 F; Age=28±11 y; BMI=23.3±3.8 Kg/m2 | 23,38 µmol | Single | 12,83 | 3µmol | Publications |