Intervention Studies for the metabolite Coumaric acid (o-) with food phytochemical Cranberry (Poly)phenols
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cranberry (Poly)phenols | Coumaric acid (o-) | Human | Plasma | Gut microbiota metabolite | 450 mL of cranberry drink | food | 10 | Healthy; Age=18-35 y | 641,05 µmol | Single | 2,9±1,1 (SEM) | 6±1 (SEM) | 103 | (0-24h) | Publications | ||||||
| Cranberry (Poly)phenols | Coumaric acid (o-) | Human | Plasma | Gut microbiota metabolite | 450 mL of cranberry drink | food | 10 | Healthy; Age=18-35 y | 1233,51 µmol | Single | 6,2±2,4 (SEM) | 6±1 (SEM) | 99 | (0-24h) | Publications | ||||||
| Cranberry (Poly)phenols | Coumaric acid (o-) | Human | Plasma | Gut microbiota metabolite | 450 mL of cranberry drink | food | 10 | Healthy; Age=18-35 y | 1940,38 µmol | Single | 3,8±1 (SEM) | 5±1 (SEM) | 97 | (0-24h) | Publications | ||||||
| Cranberry (Poly)phenols | Coumaric acid (o-) | Human | Plasma | Gut microbiota metabolite | 450 mL of cranberry drink | food | 10 | Healthy; Age=18-35 y | 2404,32 µmol | Single | 4,4±0,9 (SEM) | 6±1 (SEM) | 97 | (0-24h) | Publications | ||||||
| Cranberry (Poly)phenols | Coumaric acid (o-) | Human | Plasma | Gut microbiota metabolite | 450 mL of cranberry drink | food | 10 | Healthy; Age=18-35 y | 2993,64 µmol | Single | 2,3±0,6 (SEM) | 7±1 (SEM) | 110 | (0-24h) | Publications | ||||||
| Cranberry (Poly)phenols | Coumaric acid (o-) | Human | Urine | Gut microbiota metabolite | 450 mL of cranberry juice | food | 10 | Healthy; M; Age=18-35 y | 1233,51 µmol | Single | 0,00 | 4µg(0-24h)±1 (SEM) (4µg(0-24h)) | Publications | ||||||||
| Cranberry (Poly)phenols | Coumaric acid (o-) | Human | Urine | Gut microbiota metabolite | 9 g of cranberry powder + 500 mL water | food | 45 | Healthy; M; Age=18-45 y | 951,00 µmol | Single | 0,02 | 0.2µmol(0-24h)±0,1 (SEM) (0.2µmol(0-24h)) | Publications | ||||||||
| Cranberry (Poly)phenols | Coumaric acid (o-) | Human | Urine | Gut microbiota metabolite | 9 g of cranberry powder + 500 mL water | food | 45 | Healthy; M; Age=18-45 y | 951,00 µmol | Multiple | 1 month (1 dose daily) | 0,03 | 0.3µmol(0-24h)±0,1 (SEM) (0.3µmol(0-24h)) | Publications |