Intervention Studies for the metabolite Dihydrocoumaroylquinic acid with food phytochemical Coffee Chlorogenic acids
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Coffee Chlorogenic acids | Dihydrocoumaroylquinic acid | Human | Plasma; Urine | Gut microbiota metabolite | 250 mL of coffee (3.5 g of green-roasted coffee) | food | 12 | Healthy; 7 M (Age=27.86±3.48 y; BMI=23.42±2.52 kg/m2); 5 F (Age=28.88±3.56 y; BMI=22.43±3.33 kg/m2) | 760.6 μmol | Single | 8,4±0,7 (SD) | 0,011±0,008 (SD) | 0,03 | (0-12h) | 0,13 | 1.0µmol(0-24h)±0,4 (SD) (1.0µmol(0-24h)) | Publications | ||||
| Coffee Chlorogenic acids | Dihydrocoumaroylquinic acid | Human | Plasma; Urine | Gut microbiota metabolite | 250 mL of coffee (3.5 g of green-roasted coffee) | food | 12 | Healthy; 7 M (Age=27.86±3.48 y; BMI=23.42±2.52 kg/m2); 5 F (Age=28.88±3.56 y; BMI=22.43±3.33 kg/m2) | 760.6 μmol | Single | 9,4±0,7 (SD) | 0,009±0,005 (SD) | 0,03 | (0-12h) | 0,09 | 0.7µmol(0-24h)±0,1 (SD) (0.7µmol(0-24h)) | Publications |