Intervention Studies for the metabolite Ferulic acid-4'-O-glucuronide with food phytochemical Tomato (Poly)phenols
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Tomato (Poly)phenols | Ferulic acid-4'-O-glucuronide | Human | Plasma; Urine | Host metabolism | 500 g of tomato | food | 40 | Healthy; 19 M; 21 F; Age=28±11 y; BMI=23.3±3.8 Kg/m2 | 20,38 µmol | Single | 1,3±0,9 (SD) | 144,7±114 (SD) | 249,4 | (0-24h) | 75,55 | 15.4µmol(0-24h)±11,6 (SD) (15.4µmol(0-24h)) | Publications | ||||
| Tomato (Poly)phenols | Ferulic acid-4'-O-glucuronide | Human | Plasma; Urine | Host metabolism | 500 g of tomato | food | 40 | Healthy; 19 M; 21 F; Age=28±11 y; BMI=23.3±3.8 Kg/m2 | 20,38 µmol | Single | 1±0,7 (SD) | 51,9±44,2 (SD) | 190,2 | (0-24h) | 67,21 | 13.7µmol(0-24h)±11,5 (SD) (13.7µmol(0-24h)) | Publications | ||||
| Tomato (Poly)phenols | Ferulic acid-4'-O-glucuronide | Human | Plasma; Urine | Host metabolism | 500 g of tomato | food | 40 | Healthy; 19 M; 21 F; Age=28±11 y; BMI=23.3±3.8 Kg/m2 | 20,38 µmol | Single | 1,6±2 (SD) | 146,7±154,6 (SD) | 1267,3 | (0-24h) | 45.9µmol(0-24h)±34,7 (SD) (45.9µmol(0-24h)) | Publications | |||||
| Tomato (Poly)phenols | Ferulic acid-4'-O-glucuronide | Human | Plasma; Urine | Host metabolism | 250 g of tomato sauce | food | 40 | Healthy; 19 M; 21 F; Age=28±11 y; BMI=23.3±3.8 Kg/m2 | 22,92 µmol | Single | 1,6±1 (SD) | 139,8±110,8 (SD) | 299,4 | (0-24h) | 63,27 | 14.5µmol(0-24h)±10,9 (SD) (14.5µmol(0-24h)) | Publications | ||||
| Tomato (Poly)phenols | Ferulic acid-4'-O-glucuronide | Human | Plasma; Urine | Host metabolism | 250 g of tomato sauce | food | 40 | Healthy; 19 M; 21 F; Age=28±11 y; BMI=23.3±3.8 Kg/m2 | 22,92 µmol | Single | 1,5±1,1 (SD) | 88±75,3 (SD) | 213,1 | (0-24h) | 59,78 | 13.7µmol(0-24h)±10,9 (SD) (13.7µmol(0-24h)) | Publications | ||||
| Tomato (Poly)phenols | Ferulic acid-4'-O-glucuronide | Human | Plasma; Urine | Host metabolism | 250 g of tomato sauce | food | 40 | Healthy; 19 M; 21 F; Age=28±11 y; BMI=23.3±3.8 Kg/m2 | 22,92 µmol | Single | 1,4±1,7 (SD) | 144,7±124 (SD) | 1293,8 | (0-24h) | 47.2µmol(0-24h)±40,3 (SD) (47.2µmol(0-24h)) | Publications | |||||
| Tomato (Poly)phenols | Ferulic acid-4'-O-glucuronide | Human | Plasma; Urine | Host metabolism | 250 g of tomato sauce + refined olive oil (5%) | food | 40 | Healthy; 19 M; 21 F; Age=28±11 y; BMI=23.3±3.8 Kg/m2 | 23,38 µmol | Single | 2,3±1,7 (SD) | 94,4±73,6 (SD) | 122 | (0-24h) | 57,75 | 13.5µmol(0-24h)±11,2 (SD) (13.5µmol(0-24h)) | Publications | ||||
| Tomato (Poly)phenols | Ferulic acid-4'-O-glucuronide | Human | Plasma; Urine | Host metabolism | 100g of tomato sauce without oil | food | 5 | Healthy; M; Age=25-36 y; BMI=25±1.2 kg/m2 | 2048,85 µmol | Single | 1,2 | 580±85,4 (SEM) | 118949 | (0-24h) | 0,47 | 9529.9nmol(0-24h)±1966,6 (SEM) (9529.9nmol(0-24h)) | Publications | ||||
| Tomato (Poly)phenols | Ferulic acid-4'-O-glucuronide | Human | Plasma; Urine | Host metabolism | 100g of tomato sauce with 5% virgin olive oil | food | 5 | Healthy; M; Age=25-36 y; BMI=25±1.2 kg/m2 | 1664,71 µmol | Single | 1,25 | 727±165 (SEM) | 197702 | (0-24h) | 0,70 | 11594.3±2762 µg(0-24 (SEM) (h)) | Publications | ||||
| Tomato (Poly)phenols | Ferulic acid-4'-O-glucuronide | Human | Plasma; Urine | Host metabolism | 100g of tomato sauce with 5% refined oil | food | 5 | Healthy; M; Age=25-36 y; BMI=25±1.2 kg/m2 | 1694,84 µmol | Single | 1,4 | 544±101 (SEM) | 96531 | (0-24h) | 0,43 | 7334.9nmol(0-24h)±1212,9 (SEM) (7334.9nmol(0-24h)) | Publications | ||||
| Tomato (Poly)phenols | Ferulic acid-4'-O-glucuronide | Human | Plasma; Urine | Host-gut microbiota co-metabolite | 500 g of raw tomatoes | food | 8 | Healthy; 4 F; Age=27-46 y; BMI= 23 ± 0.93 kg/m2 | 14,15 µmol | Single | 3,06 | 389±82,6 (SEM) | 134631 | (0-24h) | 25.01µmol(0-24h) (25.01µmol(0-24h)) | Publications | |||||
| Tomato (Poly)phenols | Ferulic acid-4'-O-glucuronide | Human | Plasma; Urine | Host-gut microbiota co-metabolite | 250 g of raw tomato sauce | food | 8 | Healthy; 4 F; Age=27-46 y; BMI= 23 ± 0.93 kg/m2 | 19,18 µmol | Single | 3 | 343,9±77,6 (SEM) | 184139 | (0-24h) | 26.6µmol(0-24h) (26.6µmol(0-24h)) | Publications | |||||
| Tomato (Poly)phenols | Ferulic acid-4'-O-glucuronide | Human | Plasma; Urine | Host-gut microbiota co-metabolite | 250 g of refined olive oil-enriched tomato sauce | food | 8 | Healthy; 4 F; Age=27-46 y; BMI= 23 ± 0.93 kg/m2 | 20,06 µmol | Single | 6,42 | 351,5±72 (SEM) | 139145 | (0-24h) | 41,24 | 8.27µmol(0-24h) (8.27µmol(0-24h)) | Publications | ||||
| Tomato (Poly)phenols | Ferulic acid-4'-O-glucuronide | Human | Plasma; Urine | Host-gut microbiota co-metabolite | 500 g of tomato | food | 40 | Healthy; 19 M; 21 F; Age=28±11 y; BMI=23.3±3.8 Kg/m2 | 20,38 µmol | Single | 2,6±2 (SD) | 89,1±78,1 (SD) | 875. 3 | (0-24h) | 46.3µmol(0-24h)±43,1 (SD) (46.3µmol(0-24h)) | Publications | |||||
| Tomato (Poly)phenols | Ferulic acid-4'-O-glucuronide | Human | Plasma; Urine | Host-gut microbiota co-metabolite | 250 g of tomato sauce | food | 40 | Healthy; 19 M; 21 F; Age=28±11 y; BMI=23.3±3.8 Kg/m2 | 22,92 µmol | Single | 2,9±2,2 (SD) | 102,9±108,8 (SD) | 1166,8 | (0-24h) | 33.4µmol(0-24h)±33,7 (SD) (33.4µmol(0-24h)) | Publications | |||||
| Tomato (Poly)phenols | Ferulic acid-4'-O-glucuronide | Human | Plasma; Urine | Host-gut microbiota co-metabolite | 250 g of tomato sauce + refined olive oil (5%) | food | 40 | Healthy; 19 M; 21 F; Age=28±11 y; BMI=23.3±3.8 Kg/m2 | 23,38 µmol | Single | 3,6±2,2 (SD) | 114,2±102 (SD) | 1026,4 | (0-24h) | 40.3µmol(0-24h)±43,1 (SD) (40.3µmol(0-24h)) | Publications | |||||
| Tomato (Poly)phenols | Ferulic acid-4'-O-glucuronide | Human | Plasma; Urine | Host-gut microbiota co-metabolite | 250 g of tomato sauce + refined olive oil (5%) | food | 40 | Healthy; 19 M; 21 F; Age=28±11 y; BMI=23.3±3.8 Kg/m2 | 23,38 µmol | Single | 2,8±1,6 (SD) | 188,4±172,8 (SD) | 475,8 | (0-24h) | 69,72 | 16.3µmol(0-24h)±14,2 (SD) (16.3µmol(0-24h)) | Publications | ||||
| Tomato (Poly)phenols | Ferulic acid-4'-O-glucuronide | Human | Urine | Host-gut microbiota co-metabolite | 250 g of tomato sauce + refined olive oil (5%) | food | 40 | Healthy; 19 M; 21 F; Age=28±11 y; BMI=23.3±3.8 Kg/m2 | 23,38 µmol | Single | 51.4µmol(0-24h)±49,7 (SD) (51.4µmol(0-24h)) | Publications |