Intervention Studies for the metabolite Ferulic acid-4'-sulfate with food phytochemical Coffee Chlorogenic acids
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications |
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Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Coffee Chlorogenic acids | Ferulic acid-4'-sulfate | Human | Plasma | Host metabolism | 3.6 g of ground coffee + 50 mL water | food | 15 | Healthy; Age=26.3 ± 1.6 y; BMI=23.5 ± 0.5 kg/m2 | 778,43 µmol | Single | 1 | 43,26±3,7 (SEM) | Publications | ||||||||
| Coffee Chlorogenic acids | Ferulic acid-4'-sulfate | Human | Plasma | Host metabolism | 3.6 g of ground coffee + 50 mL water | food | 15 | Healthy; Age=26.3 ± 1.6 y; BMI=23.5 ± 0.5 kg/m2 | 214,15 µmol | Single | 1 | 38,19±2,47 (SEM) | Publications | ||||||||
| Coffee Chlorogenic acids | Ferulic acid-4'-sulfate | Human | Plasma | Host metabolism | 200 mL of instant coffee beverage | food | 14 | Healthy; 7 M; 7 F; Age=29.36±8.06 y; BMI=22.95±1.72 kg/m2; Caucasians | 48,03 µmol | Single | 0,37 | 37 | 3964 | (0-15h) | Publications | ||||||
| Coffee Chlorogenic acids | Ferulic acid-4'-sulfate | Human | Plasma | Host metabolism | 200 mL of coffee + 2 bread rolls + honey | food | 14 | Healthy; 7 M; 7 F; Age=29.36±8.06 y; BMI=22.95±1.72 kg/m2; Caucasians | 48,03 µmol | Single | 1,13 | 26 | 5298 | (0-15h) | Publications | ||||||
| Coffee Chlorogenic acids | Ferulic acid-4'-sulfate | Human | Plasma | Host metabolism | 200 mL of coffee + 1 bread roll + peanut butter | food | 14 | Healthy; 7 M; 7 F; Age=29.36±8.06 y; BMI=22.95±1.72 kg/m2; Caucasians | 48,03 µmol | Single | 1,18 | 29 | 5216 | (0-15h) | Publications | ||||||
| Coffee Chlorogenic acids | Ferulic acid-4'-sulfate | Human | Plasma | Host metabolism | 350 mL of coffee (18.66 g of coffee) | food | 13 | Healthy; 6 F (Age=24–28 y); 7 M (Age=27–30 y) | 519,07 µmol | Single | 1 | 0,226±0,113 (SD) | Publications | ||||||||
| Coffee Chlorogenic acids | Ferulic acid-4'-sulfate | Human | Plasma; Urine | Host metabolism | 250 mL of coffee (3.5 g of green-roasted coffee) | food | 12 | Healthy; 7 M (Age=27.86±3.48 y; BMI=23.42±2.52 kg/m2); 5 F (Age=28.88±3.56 y; BMI=22.43±3.33 kg/m2) | 760.6 μmol | Single | 0,7±0,2 (SD) | 0,02±0,01 (SD) | 0,03 | (0-12h) | 1,05 | 8µmol(0-24h)±1 (SD) (8µmol(0-24h)) | Publications | ||||
| Coffee Chlorogenic acids | Ferulic acid-4'-sulfate | Human | Plasma; Urine | Host metabolism | 200 mL of instant coffee beverage | food | 11 | healthy; 8 M; 3 F; Age=19-35 y; BMI=24.3±2.3 kg/m2 | 412,00 µmol | Single | 0,5±(0.5;0.5) (IR) | 65±(61;90) (IR) | 2,40 | 9.9µmol(0-24h)±(7.3;13.7) (IR) (9.9µmol(0-24h)) | Publications | ||||||
| Coffee Chlorogenic acids | Ferulic acid-4'-sulfate | Human | Plasma; Urine | Host metabolism | 200 mL of instant coffee beverage | food | 11 | healthy; 8 M; 3 F; Age=19-35 y; BMI=24.3±2.3 kg/m2 | 635,00 µmol | Single | 0,5±(0.5;0.5) (IR) | 126±(111;195) (IR) | 2,30 | 14.4µmol(0-24h)±(12.3;26.7) (IR) (14.4µmol(0-24h)) | Publications | ||||||
| Coffee Chlorogenic acids | Ferulic acid-4'-sulfate | Human | Plasma; Urine | Host metabolism | 200 mL of instant coffee beverage | food | 11 | healthy; 8 M; 3 F; Age=19-35 y; BMI=24.3±2.3 kg/m2 | 795,00 µmol | Single | 0,5±(0.5;0.5) (IR) | 68±(47;94) (IR) | 2,00 | 16.1µmol(0-24h)±(12.3;24.8) (IR) (16.1µmol(0-24h)) | Publications |