Intervention Studies for the metabolite caffeic acid-4'-O-glucuronide with food phytochemical Cranberry (Poly)phenols
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cranberry (Poly)phenols | caffeic acid-4'-O-glucuronide | Human | Plasma | Host metabolism | 450 mL of cranberry juice | food | 10 | Healthy; M; Age=18-32 y | 641,00 µmol | Single | 1 | 25 | Publications | ||||||||
| Cranberry (Poly)phenols | caffeic acid-4'-O-glucuronide | Human | Plasma | Host metabolism | 450 mL of cranberry juice | food | 10 | Healthy; M; Age=18-32 y | 1233,00 µmol | Single | 1 | 60 | Publications | ||||||||
| Cranberry (Poly)phenols | caffeic acid-4'-O-glucuronide | Human | Plasma | Host metabolism | 450 mL of cranberry juice | food | 10 | Healthy; M; Age=18-32 y | 1940,00 µmol | Single | 1 | 70 | Publications | ||||||||
| Cranberry (Poly)phenols | caffeic acid-4'-O-glucuronide | Human | Plasma | Host metabolism | 450 mL of cranberry juice | food | 10 | Healthy; M; Age=18-32 y | 2404,00 µmol | Single | 1 | 110 | Publications | ||||||||
| Cranberry (Poly)phenols | caffeic acid-4'-O-glucuronide | Human | Plasma | Host metabolism | 450 mL of cranberry juice | food | 10 | Healthy; M; Age=18-32 y | 2993,00 µmol | Single | 1 | 120 | Publications | ||||||||
| Cranberry (Poly)phenols | caffeic acid-4'-O-glucuronide | Human | Plasma | Host-gut microbiota co-metabolite | 450 mL of cranberry drink | food | 10 | Healthy; Age=18-35 y | 641,05 µmol | Single | 7,9±3,2 (SEM) | 33±6 (SEM) | 320 | (0-24h) | Publications | ||||||
| Cranberry (Poly)phenols | caffeic acid-4'-O-glucuronide | Human | Plasma | Host-gut microbiota co-metabolite | 450 mL of cranberry drink | food | 10 | Healthy; Age=18-35 y | 1233,51 µmol | Single | 9,4±3,7 (SEM) | 59±8 (SEM) | 380 | (0-24h) | Publications | ||||||
| Cranberry (Poly)phenols | caffeic acid-4'-O-glucuronide | Human | Plasma | Host-gut microbiota co-metabolite | 450 mL of cranberry drink | food | 10 | Healthy; Age=18-35 y | 1940,38 µmol | Single | 7,1±3,3 (SEM) | 86±14 (SEM) | 457 | (0-24h) | Publications | ||||||
| Cranberry (Poly)phenols | caffeic acid-4'-O-glucuronide | Human | Plasma | Host-gut microbiota co-metabolite | 450 mL of cranberry drink | food | 10 | Healthy; Age=18-35 y | 2404,32 µmol | Single | 9,4±3,7 (SEM) | 110±24 (SEM) | 531 | (0-24h) | Publications | ||||||
| Cranberry (Poly)phenols | caffeic acid-4'-O-glucuronide | Human | Plasma | Host-gut microbiota co-metabolite | 450 mL of cranberry drink | food | 10 | Healthy; Age=18-35 y | 2993,64 µmol | Single | 4,8±2,6 (SEM) | 119±15 (SEM) | 562 | (0-24h) | Publications | ||||||
| Cranberry (Poly)phenols | caffeic acid-4'-O-glucuronide | Human | Urine | Host-gut microbiota co-metabolite | 450 mL of cranberry juice | food | 10 | Healthy; M; Age=18-35 y | 1233,51 µmol | Single | 0,00 | 18µg(0-24h)±4 (SEM) (18µg(0-24h)) | Publications | ||||||||
| Cranberry (Poly)phenols | caffeic acid-4'-O-glucuronide | Human | Urine | Host-gut microbiota co-metabolite | 9 g of cranberry powder + 500 mL water | food | 45 | Healthy; M; Age=18-45 y | 951,00 µmol | Single | 0,26 | 2.5µmol(0-24h)±0,5 (SEM) (2.5µmol(0-24h)) | Publications | ||||||||
| Cranberry (Poly)phenols | caffeic acid-4'-O-glucuronide | Human | Urine | Host-gut microbiota co-metabolite | 9 g of cranberry powder + 500 mL water | food | 45 | Healthy; M; Age=18-45 y | 951,00 µmol | Multiple | 1 month (1 dose daily) | 0,24 | 2.3µmol(0-24h)±0,4 (SEM) (2.3µmol(0-24h)) | Publications |