Intervention Studies for the metabolite Caffeic acid glucuronide with food phytochemical Tomato (Poly)phenols
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Tomato (Poly)phenols | Caffeic acid glucuronide | Human | Plasma; Urine | Host metabolism | 500 g of raw tomatoes | food | 8 | Healthy; 4 F; Age=27-46 y; BMI= 23 ± 0.93 kg/m2 | 14,15 µmol | Single | 1,67 | 6,2±1,5 (SEM) | 1141 | (0-24h) | 1,90 | 0.269µmol(0-24h) (0.269µmol(0-24h)) | Publications | ||||
| Tomato (Poly)phenols | Caffeic acid glucuronide | Human | Plasma; Urine | Host metabolism | 250 g of refined olive oil-enriched tomato sauce | food | 8 | Healthy; 4 F; Age=27-46 y; BMI= 23 ± 0.93 kg/m2 | 20,06 µmol | Single | 1,5 | 4,1±0,5 (SEM) | 689 | (0-24h) | 0,59 | 0.12µmol(0-24h) (0.12µmol(0-24h)) | Publications | ||||
| Tomato (Poly)phenols | Caffeic acid glucuronide | Human | Plasma; Urine | Host-gut microbiota co-metabolite | 250 g of raw tomato sauce | food | 8 | Healthy; 4 F; Age=27-46 y; BMI= 23 ± 0.93 kg/m2 | 19,18 µmol | Single | 2,5 | 5±2,7 (SEM) | 835 | (0-24h) | 1,16 | 0.2µmol(0-24h) (0.2µmol(0-24h)) | Publications | ||||
| Tomato (Poly)phenols | Caffeic acid glucuronide | Human | Urine | Host-gut microbiota co-metabolite | 500 g of tomato | food | 40 | Healthy; 19 M; 21 F; Age=28±11 y; BMI=23.3±3.8 Kg/m2 | 20,38 µmol | Single | 14,72 | 3µmol(0-24h) (SD) (3µmol(0-24h)) | Publications | ||||||||
| Tomato (Poly)phenols | Caffeic acid glucuronide | Human | Urine | Host-gut microbiota co-metabolite | 250 g of tomato sauce | food | 40 | Healthy; 19 M; 21 F; Age=28±11 y; BMI=23.3±3.8 Kg/m2 | 22,92 µmol | Single | 13,09 | 3µmol | Publications | ||||||||
| Tomato (Poly)phenols | Caffeic acid glucuronide | Human | Urine | Host-gut microbiota co-metabolite | 250 g of tomato sauce + refined olive oil (5%) | food | 40 | Healthy; 19 M; 21 F; Age=28±11 y; BMI=23.3±3.8 Kg/m2 | 23,38 µmol | Single | 26,52 | 6.2µmol(0-24h) (6.2µmol(0-24h)) | Publications | ||||||||
| Tomato (Poly)phenols | Caffeic acid glucuronide | Human | Urine | Host-gut microbiota co-metabolite | 100g of tomato sauce without oil | food | 5 | Healthy; M; Age=25-36 y; BMI=25±1.2 kg/m2 | 2048,85 µmol | Single | 0,00 | 31.2nmol(0-24h)±14,6 (SEM) (31.2nmol(0-24h)) | Publications | ||||||||
| Tomato (Poly)phenols | Caffeic acid glucuronide | Human | Urine | Host-gut microbiota co-metabolite | 100g of tomato sauce with 5% virgin olive oil | food | 5 | Healthy; M; Age=25-36 y; BMI=25±1.2 kg/m2 | 1664,71 µmol | Single | 0,00 | 47.9nmol(0-24h)±19,6 (SEM) (47.9nmol(0-24h)) | Publications | ||||||||
| Tomato (Poly)phenols | Caffeic acid glucuronide | Human | Urine | Host-gut microbiota co-metabolite | 100g of tomato sauce with 5% refined oil | food | 5 | Healthy; M; Age=25-36 y; BMI=25±1.2 kg/m2 | 1694,84 µmol | Single | 0,00 | 42.8nmol(0-24h)±26,6 (SEM) (42.8nmol(0-24h)) | Publications |