Intervention Studies for the metabolite Methylferulic acid with food phytochemical Coffee Chlorogenic acids
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Coffee Chlorogenic acids | Methylferulic acid | Human | Plasma | Host metabolism | 250 mL of coffee (3.5 g of green-roasted coffee) | food | 12 | Healthy; 7 M (Age=27.86±3.48 y; BMI=23.42±2.52 kg/m2); 5 F (Age=28.88±3.56 y; BMI=22.43±3.33 kg/m2) | 760.6 μmol | Single | 0,7±0,3 (SD) | 0,008±0,002 (SD) | 0,02 | (0-12h) | Publications | ||||||
| Coffee Chlorogenic acids | Methylferulic acid | Human | Plasma | Host metabolism | 400 mL of istant coffee | food | 9 | healthy; 4 M, 5 F; Age: 27-41 y | 900,00 µmol | Single | 1 | 496±110 (SD) | Publications | ||||||||
| Coffee Chlorogenic acids | Methylferulic acid | Human | Plasma | Host metabolism | 200 mL of instant coffee beverage | food | 14 | Healthy; 7 M; 7 F; Age=29.36±8.06 y; BMI=22.95±1.72 kg/m2; Caucasians | 48,03 µmol | Single | 0,28 | 61 | 15045 | (0-15h) | Publications | ||||||
| Coffee Chlorogenic acids | Methylferulic acid | Human | Plasma | Host metabolism | 200 mL of coffee + 2 bread rolls + honey | food | 14 | Healthy; 7 M; 7 F; Age=29.36±8.06 y; BMI=22.95±1.72 kg/m2; Caucasians | 48,03 µmol | Single | 0,92 | 44 | 11973 | (0-15h) | Publications | ||||||
| Coffee Chlorogenic acids | Methylferulic acid | Human | Plasma | Host metabolism | 200 mL of coffee + 1 bread roll + peanut butter | food | 14 | Healthy; 7 M; 7 F; Age=29.36±8.06 y; BMI=22.95±1.72 kg/m2; Caucasians | 48,03 µmol | Single | 0,98 | 44 | 13743 | (0-15h) | Publications | ||||||
| Coffee Chlorogenic acids | Methylferulic acid | Human | Plasma | Host metabolism | 3.6 g of ground coffee + 50 mL water | food | 15 | Healthy; Age=26.3 ± 1.6 y; BMI=23.5 ± 0.5 kg/m2 | 778,43 µmol | Single | 1 | 96,41±6,82 (SEM) | Publications | ||||||||
| Coffee Chlorogenic acids | Methylferulic acid | Human | Plasma | Host metabolism | 3.6 g of ground coffee + 50 mL water | food | 15 | Healthy; Age=26.3 ± 1.6 y; BMI=23.5 ± 0.5 kg/m2 | 214,15 µmol | Single | 1 | 113,81±4,91 (SEM) | Publications |