Intervention Studies for the metabolite 3-Caffeoylquinic acid lactone-sulfate with food phytochemical Coffee Chlorogenic acids
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Coffee Chlorogenic acids | 3-Caffeoylquinic acid lactone-sulfate | Human | Plasma; Urine | Host metabolism | 200 mL of instant coffee beverage | food | 11 | healthy; 8 M; 3 F; Age=19-35 y; BMI=24.3±2.3 kg/m2 | 412,00 µmol | Single | 0,5±(0.5;0.75) (IR) | 27±(20;35) (IR) | 26 | (0-24h) | 0,5±(0.3;0.5) (IR) | 3,00 | 1.01µmol(0-24h)±(0.9;1.3) (IR) (1.01µmol(0-24h)) | Publications | |||
| Coffee Chlorogenic acids | 3-Caffeoylquinic acid lactone-sulfate | Human | Plasma; Urine | Host metabolism | 200 mL of instant coffee beverage | food | 11 | healthy; 8 M; 3 F; Age=19-35 y; BMI=24.3±2.3 kg/m2 | 635,00 µmol | Single | 0,5±(0.5;0.5) (IR) | 54±(35;75) (IR) | 69 | (0-24h) | 0,5±(0.5;0.6) (IR) | 2,30 | 1.0µmol(0-24h)±(10.;1.4) (IR) (1.0µmol(0-24h)) | Publications | |||
| Coffee Chlorogenic acids | 3-Caffeoylquinic acid lactone-sulfate | Human | Plasma; Urine | Host metabolism | 200 mL of instant coffee beverage | food | 11 | healthy; 8 M; 3 F; Age=19-35 y; BMI=24.3±2.3 kg/m2 | 795,00 µmol | Single | 0,5±(0.5;0.5) (IR) | 20±(16;29) (IR) | 21 | (0-24h) | 0,3±(0.2;0.5) (IR) | 3,00 | 0.7µmol(0-24h)±(0.6;0.8) (IR) (0.7µmol(0-24h)) | Publications | |||
| Coffee Chlorogenic acids | 3-Caffeoylquinic acid lactone-sulfate | Human | Plasma; Urine | Host metabolism | 200 mL of coffee (3.4 g of instant powder) | food | 11 | Healthy; 8 M; 3 F; Age=19-35 y; BMI=24.3±2.3 kg/m2 | 412,00 µmol | Single | 0,6±0,1 (SEM) | 27±3 (SEM) | 30,1 | (0-24h) | 0,5±0,1 (SEM) | 0,27 | 1.1µmol±0,1 (0-24h) (SEM) ((0-24h)) | Publications |