Intervention Studies for the metabolite 4-Caffeoylquinic acid lactone-sulfate with food phytochemical Coffee Chlorogenic acids
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Coffee Chlorogenic acids | 4-Caffeoylquinic acid lactone-sulfate | Human | Plasma; Urine | Host metabolism | 200 mL of instant coffee beverage | food | 11 | healthy; 8 M; 3 F; Age=19-35 y; BMI=24.3±2.3 kg/m2 | 412,00 µmol | Single | 0,5±(0.5;0.9) (IR) | 21±(15;26) (IR) | 21 | (0-24h) | 0,5±(0.4;05) (IR) | 3,60 | 0.81µmol(0-24h)±(0.7;1.1) (IR) (0.81µmol(0-24h)) | Publications | |||
| Coffee Chlorogenic acids | 4-Caffeoylquinic acid lactone-sulfate | Human | Plasma; Urine | Host metabolism | 200 mL of instant coffee beverage | food | 11 | healthy; 8 M; 3 F; Age=19-35 y; BMI=24.3±2.3 kg/m2 | 635,00 µmol | Single | 0,5±(0.5;0.5) (IR) | 51±(30;72) (IR) | 72 | (0-24h) | 0,5±(0.5;0.6) (IR) | 2,60 | 0.8µmol(0-24h)±(07.;0.9) (IR) (0.8µmol(0-24h)) | Publications | |||
| Coffee Chlorogenic acids | 4-Caffeoylquinic acid lactone-sulfate | Human | Plasma; Urine | Host metabolism | 200 mL of instant coffee beverage | food | 11 | healthy; 8 M; 3 F; Age=19-35 y; BMI=24.3±2.3 kg/m2 | 795,00 µmol | Single | 0,5±(0.5;0.5) (IR) | 18±(13;22) (IR) | 18 | (0-24h) | 0,3±(0.1;06) (IR) | 3,30 | 0.5µmol(0-24h)±(0.5;0.6) (IR) (0.5µmol(0-24h)) | Publications | |||
| Coffee Chlorogenic acids | 4-Caffeoylquinic acid lactone-sulfate | Human | Plasma; Urine | Host metabolism | 200 mL of coffee (3.4 g of instant powder) | food | 11 | Healthy; 8 M; 3 F; Age=19-35 y; BMI=24.3±2.3 kg/m2 | 412,00 µmol | Single | 0,7±0,1 (SEM) | 21±4 (SEM) | 23,1 | (0-24h) | 0,4±0,1 (SEM) | 0,24 | 1.0µmol(0-24h)±0,1 (SEM) (1.0µmol(0-24h)) | Publications |