Intervention Studies for the metabolite artepillin C-4-O-β-D-glucuronide with food phytochemical Artepillin C
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Artepillin C | artepillin C-4-O-β-D-glucuronide | Human | Plasma | Host metabolism | 3 capsules containing 360 mg of brazilian green propolis | extract | 12 | Healthy; 6 M; 6 F; Age F= 30.0 ± 6.5 y; age M=34.8 ± 9.5 y; BMI F=20.3 ± 0.9 kg/m2; BMI M= 21.6 ± 1.4 kg/m2 | 1196,01 µmol | Single | 1,5 | 1121±399 (SD) | 5701 | (0-24h) | Publications |