Intervention Studies for the metabolite p-Hydroxybenzaldehyde with food phytochemical Coffee Chlorogenic acids
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Coffee Chlorogenic acids | p-Hydroxybenzaldehyde | Human | Plasma | Host-gut microbiota co-metabolite | 1 cup of coffee | food | 21 | Healthy; 11 F; 10 M; Age=22.9 ± 0.5 y; BMI: 22.3 ± 1.7 kg/m2 | 204,90 µmol | Multiple | 1 month (1 daily dose) | 7,7±1,3 (SEM) | 116,4±16,1 (SEM) | 1025 | (0-24h) | Publications | |||||
| Coffee Chlorogenic acids | p-Hydroxybenzaldehyde | Human | Plasma | Host-gut microbiota co-metabolite | 3 cups of coffee | food | 21 | Healthy; 11 F; 10 M; Age=22.9 ± 0.5 y; BMI: 22.3 ± 1.7 kg/m2 | 614,60 µmol | Multiple | 1 month (3 dose daily) | 4,5±0,7 (SEM) | 146,5±35,7 (SEM) | 1286,6 | (0-24h) | Publications | |||||
| Coffee Chlorogenic acids | p-Hydroxybenzaldehyde | Human | Plasma | Host-gut microbiota co-metabolite | 1 cup of coffee + 2 cocoa products containing coffee | food | 21 | Healthy; 11 F; 10 M; Age=22.9 ± 0.5 y; BMI: 22.3 ± 1.7 kg/m2 | 296,00 µmol | Multiple | 1 month (2 dose daily) | 6,1±1,1 (SEM) | 112,4±19,9 (SEM) | 790,5 | (0-24h) | Publications |