Intervention Studies for the metabolite Coumaric acid-4'-sulfate with food phytochemical Olive oil (Poly)phenols
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Olive oil (Poly)phenols | Coumaric acid-4'-sulfate | Human | Plasma | Host-gut microbiota co-metabolite | 30 mL of virgin olive oil | food | 13 | Healthy; 7 M; 6 F; Age= 25-69 y; BMI M=26.7±1.9 kg/m2; BMI F=24.9±1.5 kg/m2 | 13,04 µmol | Single | 1,1±0,6 (SD) | 222 | (0-5h) | ||||||||
| Olive oil (Poly)phenols | Coumaric acid-4'-sulfate | Human | Plasma | Host-gut microbiota co-metabolite | 30 mL of enriched virgin olive oil | food | 13 | Healthy; 7 M; 6 F; Age= 25-69 y; BMI M=26.7±1.9 kg/m2; BMI F=24.9±1.5 kg/m2 | 20,19 µmol | Single | 1,19±0,88 (SD) | 271 | (0-5h) |