Intervention Studies for the metabolite 3-(3′-Hydroxyphenyl)propionic acid-glucuronide with food phytochemical Coffee Chlorogenic acids
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Coffee Chlorogenic acids | 3-(3′-Hydroxyphenyl)propionic acid-glucuronide | Human | Urine | Host-gut microbiota co-metabolite | 1 cup of coffee | food | 21 | Healthy; 11 F; 10 M; Age=22.9 ± 0.5 y; BMI: 22.3 ± 1.7 kg/m2 | 204,90 µmol | Multiple | 1 month (1 daily dose) | 0,36 | 0.74µmol(0-24h)±0,09 (SEM) (0.74µmol(0-24h)) | Publications | |||||||
| Coffee Chlorogenic acids | 3-(3′-Hydroxyphenyl)propionic acid-glucuronide | Human | Urine | Host-gut microbiota co-metabolite | 3 cups of coffee | food | 21 | Healthy; 11 F; 10 M; Age=22.9 ± 0.5 y; BMI: 22.3 ± 1.7 kg/m2 | 614,60 µmol | Multiple | 1 month (3 dose daily) | 0,31 | 1.89µmol(0-24h)±0,17 (SEM) (1.89µmol(0-24h)) | Publications | |||||||
| Coffee Chlorogenic acids | 3-(3′-Hydroxyphenyl)propionic acid-glucuronide | Human | Urine | Host-gut microbiota co-metabolite | 1 cup of coffee + 2 cocoa products containing coffee | food | 21 | Healthy; 11 F; 10 M; Age=22.9 ± 0.5 y; BMI: 22.3 ± 1.7 kg/m2 | 296,00 µmol | Multiple | 1 month (2 dose daily) | 0,46 | 1.36µmol(0-24h)±0,15 (SEM) (1.36µmol(0-24h)) | Publications |