Intervention Studies for the metabolite 4-O-Caffeoylquinic acid with food phytochemical 4-O-Caffeoylquinic acid
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 4-O-Caffeoylquinic acid | 4-O-Caffeoylquinic acid | Human | Plasma | Unchanged | 3.6 g of ground coffee + 50 mL water | food | 15 | Healthy; Age=26.3 ± 1.6 y; BMI=23.5 ± 0.5 kg/m2 | 778,43 µmol | Single | 1 | 7,68±0,78 (SEM) | Publications | ||||||||
| 4-O-Caffeoylquinic acid | 4-O-Caffeoylquinic acid | Human | Plasma | Unchanged | 3.6 g of ground coffee + 50 mL water | food | 15 | Healthy; Age=26.3 ± 1.6 y; BMI=23.5 ± 0.5 kg/m2 | 214,15 µmol | Single | 1 | 5,35±0,5 (SEM) | Publications | ||||||||
| 4-O-Caffeoylquinic acid | 4-O-Caffeoylquinic acid | Human | Plasma; Urine | Unchanged | 200 g of sous-vide artichokes | food | 8 | Healthy; 5 F; 3 M; Age=26.4±2.8; BMI: 22.8±2.5 kg/m2 | 5714,60 µmol | Single | 25 | 151 | (0-24h) | 0,01 | 0.3µmol(0-24h) (0.3µmol(0-24h)) | Publications | |||||
| 4-O-Caffeoylquinic acid | 4-O-Caffeoylquinic acid | Human | Serum | Unchanged | 480 mg of green coffee bean extract | extract | 15 | Healthy; M | 130,96 µmol | Single | 1 | 6,84±3,13 (SD) | 16,1 | (0-4h) | Publications | ||||||
| 4-O-Caffeoylquinic acid | 4-O-Caffeoylquinic acid | Human | Urine | Unchanged | 250 mL of coffee (3.5 g of green-roasted coffee) | food | 12 | Healthy; 7 M (Age=27.86±3.48 y; BMI=23.42±2.52 kg/m2); 5 F (Age=28.88±3.56 y; BMI=22.43±3.33 kg/m2) | 760.6 μmol | Single | 0,01 | 0.11µmol(0-24h)±0,04 (SD) (0.11µmol(0-24h)) | Publications |