Intervention Studies for the metabolite 4-Feruloylquinic acid with food phytochemical 4-Feruloylquinic acid
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 4-Feruloylquinic acid | 4-Feruloylquinic acid | Human | Plasma | Unchanged | 3.6 g of ground coffee + 50 mL water | food | 15 | Healthy; Age=26.3 ± 1.6 y; BMI=23.5 ± 0.5 kg/m2 | 778,43 µmol | Single | 1 | 8,4±0,81 (SEM) | Publications | ||||||||
| 4-Feruloylquinic acid | 4-Feruloylquinic acid | Human | Plasma | Unchanged | 3.6 g of ground coffee + 50 mL water | food | 15 | Healthy; Age=26.3 ± 1.6 y; BMI=23.5 ± 0.5 kg/m2 | 214,15 µmol | Single | 1 | 8,24±0,82 (SEM) | Publications | ||||||||
| 4-Feruloylquinic acid | 4-Feruloylquinic acid | Human | Plasma | Unchanged | 200 mL of instant coffee beverage | food | 14 | Healthy; 7 M; 7 F; Age=29.36±8.06 y; BMI=22.95±1.72 kg/m2; Caucasians | 48,03 µmol | Single | 0,60 | 9 | 82 | (0-15h) | Publications | ||||||
| 4-Feruloylquinic acid | 4-Feruloylquinic acid | Human | Plasma | Unchanged | 200 mL of coffee + 2 bread rolls + honey | food | 14 | Healthy; 7 M; 7 F; Age=29.36±8.06 y; BMI=22.95±1.72 kg/m2; Caucasians | 48,03 µmol | Single | 1,55 | 7 | 9 | (0-15h) | Publications | ||||||
| 4-Feruloylquinic acid | 4-Feruloylquinic acid | Human | Plasma | Unchanged | 200 mL of coffee + 1 bread roll + peanut butter | food | 14 | Healthy; 7 M; 7 F; Age=29.36±8.06 y; BMI=22.95±1.72 kg/m2; Caucasians | 48,03 µmol | Single | 1,38 | 9 | 93 | (0-15h) | Publications | ||||||
| 4-Feruloylquinic acid | 4-Feruloylquinic acid | Human | Plasma; Urine | Unchanged | 200 mL of instant coffee beverage | food | 11 | healthy; 8 M; 3 F; Age=19-35 y; BMI=24.3±2.3 kg/m2 | 412,00 µmol | Single | 1±(0.5;1.0) (IR) | 14±(8.4;18) (IR) | 20 | (0-24h) | 0,8±(0.6;0.9) (IR) | 5,30 | 1.2µmol(0-24h)±(0.9;1.4) (IR) (1.2µmol(0-24h)) | Publications | |||
| 4-Feruloylquinic acid | 4-Feruloylquinic acid | Human | Plasma; Urine | Unchanged | 200 mL of instant coffee beverage | food | 11 | healthy; 8 M; 3 F; Age=19-35 y; BMI=24.3±2.3 kg/m2 | 635,00 µmol | Single | 1±(0.8;1.0) (IR) | 24±(21;45) (IR) | 55 | (0-24h) | 1±(0.8;1.2) (IR) | 2,70 | 1.1µmol(0-24h)±(0.8;1.7) (IR) (1.1µmol(0-24h)) | Publications | |||
| 4-Feruloylquinic acid | 4-Feruloylquinic acid | Human | Plasma; Urine | Unchanged | 200 mL of instant coffee beverage | food | 11 | healthy; 8 M; 3 F; Age=19-35 y; BMI=24.3±2.3 kg/m2 | 795,00 µmol | Single | 1±(0.5;1.3) (IR) | 9±(7.7;13) (IR) | 19 | (0-24h) | 0,9±(0.8;1.4) (IR) | 3,10 | 0.7µmol(0-24h)±(0.4;0.8) (IR) (0.7µmol(0-24h)) | Publications | |||
| 4-Feruloylquinic acid | 4-Feruloylquinic acid | Human | Plasma; Urine | Unchanged | 250 mL of coffee (3.5 g of green-roasted coffee) | food | 12 | Healthy; 7 M (Age=27.86±3.48 y; BMI=23.42±2.52 kg/m2); 5 F (Age=28.88±3.56 y; BMI=22.43±3.33 kg/m2) | 760.6 μmol | Single | 0,9±0,3 (SD) | 0,02±0,01 (SD) | 0,03 | (0-12h) | 0,16 | 1.2µmol(0-24h)±0,1 (SD) (1.2µmol(0-24h)) | Publications | ||||
| 4-Feruloylquinic acid | 4-Feruloylquinic acid | Human | Plasma; Urine | Unchanged | 1 cup of coffee | food | 21 | Healthy; 11 F; 10 M; Age=22.9 ± 0.5 y; BMI: 22.3 ± 1.7 kg/m2 | 204,90 µmol | Multiple | 1 month (1 daily dose) | 0,6±0,1 (SEM) | 25±3,7 (SEM) | 60,5 | (0-24h) | 0,04 | 0.08±0,01 µmol(0-24h) (SEM) (µmol(0-24h)) | Publications | |||
| 4-Feruloylquinic acid | 4-Feruloylquinic acid | Human | Plasma; Urine | Unchanged | 3 cups of coffee | food | 21 | Healthy; 11 F; 10 M; Age=22.9 ± 0.5 y; BMI: 22.3 ± 1.7 kg/m2 | 614,60 µmol | Multiple | 1 month (3 dose daily) | 3±0,6 (SEM) | 27,6±2,4 (SEM) | 111,5 | (0-24h) | 0,04 | 0.25µmol(0-24h)±0,02 (SEM) (0.25µmol(0-24h)) | Publications | |||
| 4-Feruloylquinic acid | 4-Feruloylquinic acid | Human | Plasma; Urine | Unchanged | 1 cup of coffee + 2 cocoa products containing coffee | food | 21 | Healthy; 11 F; 10 M; Age=22.9 ± 0.5 y; BMI: 22.3 ± 1.7 kg/m2 | 296,00 µmol | Multiple | 1 month (2 dose daily) | 1,6±0,4 (SEM) | 22,3±2,5 (SEM) | 68,7 | (0-24h) | 0,04 | 0.12µmol(0-24h)±0,01 (SEM) (0.12µmol(0-24h)) | Publications | |||
| 4-Feruloylquinic acid | 4-Feruloylquinic acid | Human | Plasma; Urine | Unchanged | 200 mL of coffee (3.4 g of instant powder) | food | 11 | Healthy; 8 M; 3 F; Age=19-35 y; BMI=24.3±2.3 kg/m2 | 412,00 µmol | Single | 0±0,1 (SEM) | 14±2 (SEM) | 24,5 | (0-24h) | 0,9±0,1 (SEM) | 0,27 | 1.1µmol(1-24h)±0,1 (SEM) (1.1µmol(1-24h)) | Publications | |||
| 4-Feruloylquinic acid | 4-Feruloylquinic acid | Human | Urine | Unchanged | 4.91 g of yerba mate in 250 mL water | food | 12 | Healthy; 7 M (Age=27.86±3.48 y; BMI=23.42±2.52 kg/m2); 5 F (Age=28.88±3.56 y; BMI=22.43±3.33 kg/m2) | 1118,00 µmol | Single | 0,05 | 0.506µmol(0-24h)±0,111 (SD) (0.506µmol(0-24h)) | Publications |