Intervention Studies for the metabolite 5-Feruloylquinic acid with food phytochemical 5-Feruloylquinic acid
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 5-Feruloylquinic acid | 5-Feruloylquinic acid | Human | Plasma | Unchanged | 200 mL of instant coffee beverage | food | 14 | Healthy; 7 M; 7 F; Age=29.36±8.06 y; BMI=22.95±1.72 kg/m2; Caucasians | 48,03 µmol | Single | 0,62 | 17 | 1237 | (0-15h) | Publications | ||||||
| 5-Feruloylquinic acid | 5-Feruloylquinic acid | Human | Plasma | Unchanged | 3.6 g of ground coffee + 50 mL water | food | 15 | Healthy; Age=26.3 ± 1.6 y; BMI=23.5 ± 0.5 kg/m2 | 778,43 µmol | Single | 1 | 17,9±1,44 (SEM) | Publications | ||||||||
| 5-Feruloylquinic acid | 5-Feruloylquinic acid | Human | Plasma | Unchanged | 3.6 g of ground coffee + 50 mL water | food | 15 | Healthy; Age=26.3 ± 1.6 y; BMI=23.5 ± 0.5 kg/m2 | 214,15 µmol | Single | 1 | 7,34±0,8 (SEM) | Publications | ||||||||
| 5-Feruloylquinic acid | 5-Feruloylquinic acid | Human | Plasma | Unchanged | 200 mL of coffee + 2 bread rolls + honey | food | 14 | Healthy; 7 M; 7 F; Age=29.36±8.06 y; BMI=22.95±1.72 kg/m2; Caucasians | 48,03 µmol | Single | 1,58 | 12 | 818 | (0-15h) | Publications | ||||||
| 5-Feruloylquinic acid | 5-Feruloylquinic acid | Human | Plasma | Unchanged | 200 mL of coffee + 1 bread roll + peanut butter | food | 14 | Healthy; 7 M; 7 F; Age=29.36±8.06 y; BMI=22.95±1.72 kg/m2; Caucasians | 48,03 µmol | Single | 1,27 | 14 | 932 | (0-15h) | Publications | ||||||
| 5-Feruloylquinic acid | 5-Feruloylquinic acid | Human | Plasma; Urine | Unchanged | 200 mL of instant coffee beverage | food | 11 | healthy; 8 M; 3 F; Age=19-35 y; BMI=24.3±2.3 kg/m2 | 412,00 µmol | Single | 1±(0.6;1.0) (IR) | 5±(4.5;5.9) (IR) | 7,9 | (0-24h) | 0,8±(0.6;1.0) (IR) | 3,30 | 0.8µmol(0-24h)±(0.6;1.0) (IR) (0.8µmol(0-24h)) | Publications | |||
| 5-Feruloylquinic acid | 5-Feruloylquinic acid | Human | Plasma; Urine | Unchanged | 200 mL of instant coffee beverage | food | 11 | healthy; 8 M; 3 F; Age=19-35 y; BMI=24.3±2.3 kg/m2 | 635,00 µmol | Single | 1±(0.6;1.0) (IR) | 12±(10;14) (IR) | 19 | (0-24h) | 0,8±(0.5;1.0) (IR) | 1,80 | 0.9µmol(0-24h)±(0.7;1.1) (IR) (0.9µmol(0-24h)) | Publications | |||
| 5-Feruloylquinic acid | 5-Feruloylquinic acid | Human | Plasma; Urine | Unchanged | 200 mL of instant coffee beverage | food | 11 | healthy; 8 M; 3 F; Age=19-35 y; BMI=24.3±2.3 kg/m2 | 795,00 µmol | Single | 1±(1.0;1.5) (IR) | 18±(15;22) (IR) | 38 | (0-24h) | 1,1±(0.8;1.3) (IR) | 2,20 | 1.4µmol(0-24h)±(1.1;1.6) (IR) (1.4µmol(0-24h)) | Publications | |||
| 5-Feruloylquinic acid | 5-Feruloylquinic acid | Human | Plasma; Urine | Unchanged | 250 mL of coffee (3.5 g of green-roasted coffee) | food | 12 | Healthy; 7 M (Age=27.86±3.48 y; BMI=23.42±2.52 kg/m2); 5 F (Age=28.88±3.56 y; BMI=22.43±3.33 kg/m2) | 760.6 μmol | Single | 1,2±0,4 (SD) | 0,02±0,01 (SD) | 0,04 | (0-12h) | 0,20 | 1.5µmol(0-24h)±0,3 (SD) (1.5µmol(0-24h)) | Publications | ||||
| 5-Feruloylquinic acid | 5-Feruloylquinic acid | Human | Plasma; Urine | Unchanged | 1 cup of coffee | food | 21 | Healthy; 11 F; 10 M; Age=22.9 ± 0.5 y; BMI: 22.3 ± 1.7 kg/m2 | 204,90 µmol | Multiple | 1 month (1 daily dose) | 1,2±0,1 (SEM) | 12,6±1,3 (SEM) | 38,4 | (0-24h) | 0,28 | 0.57±0,07 µmol(0-24h) (SEM) (µmol(0-24h)) | Publications | |||
| 5-Feruloylquinic acid | 5-Feruloylquinic acid | Human | Plasma; Urine | Unchanged | 3 cups of coffee | food | 21 | Healthy; 11 F; 10 M; Age=22.9 ± 0.5 y; BMI: 22.3 ± 1.7 kg/m2 | 614,60 µmol | Multiple | 1 month (3 dose daily) | 3,7±0,4 (SEM) | 14,5±1 (SEM) | 106,3 | (0-24h) | 0,19 | 1.19µmol(0-24h)±0,12 (SEM) (1.19µmol(0-24h)) | Publications | |||
| 5-Feruloylquinic acid | 5-Feruloylquinic acid | Human | Plasma; Urine | Unchanged | 1 cup of coffee + 2 cocoa products containing coffee | food | 21 | Healthy; 11 F; 10 M; Age=22.9 ± 0.5 y; BMI: 22.3 ± 1.7 kg/m2 | 296,00 µmol | Multiple | 1 month (2 dose daily) | 2,2±0,4 (SEM) | 12,2±1,3 (SEM) | 62,9 | (0-24h) | 0,22 | 0.65µmol(0-24h)±0,07 (SEM) (0.65µmol(0-24h)) | Publications | |||
| 5-Feruloylquinic acid | 5-Feruloylquinic acid | Human | Plasma; Urine | Unchanged | 200 mL of coffee (3.4 g of instant powder) | food | 11 | Healthy; 8 M; 3 F; Age=19-35 y; BMI=24.3±2.3 kg/m2 | 412,00 µmol | Single | 0±0,1 (SEM) | 6±1,5 (SEM) | 10,4 | (0-24h) | 0,8±0,1 (SEM) | 0,24 | 1.0µmol(0-24h)±0,2 (SEM) (1.0µmol(0-24h)) | Publications | |||
| 5-Feruloylquinic acid | 5-Feruloylquinic acid | Human | Urine | Unchanged | 4.91 g of yerba mate in 250 mL water | food | 12 | Healthy; 7 M (Age=27.86±3.48 y; BMI=23.42±2.52 kg/m2); 5 F (Age=28.88±3.56 y; BMI=22.43±3.33 kg/m2) | 1118,00 µmol | Single | 0,06 | 0.667µmol(0-24h)±0,134 (SD) (0.667µmol(0-24h)) | Publications |