Intervention Studies for the metabolite 7-Hydroxymatairesinol with food phytochemical 7-Hydroxymatairesinol
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 7-Hydroxymatairesinol | 7-Hydroxymatairesinol | Human | Plasma | Unchanged | Capsule of HMR lignan 70% 7-HMR | Pure compound | 12 | Menaupause; 12F; Age=50-75Y; BMI=20-35 kg/m² | 25 mg | single | 72 hours | 1 | 757,08±41.24 | Publications | |||||||
| 7-Hydroxymatairesinol | 7-Hydroxymatairesinol | Human | Plasma | Unchanged | Capsule of HMR lignan 70% 7-HMR | Pure compound | 12 | Menaupause; 12F; Age=50-75Y; BMI=20-35 kg/m² | 25 mg | multiple | 8 weeks | Publications | |||||||||
| 7-Hydroxymatairesinol | 7-Hydroxymatairesinol | Human | Plasma | Unchanged | Capsule of HMR lignan 70% 7-HMR | Pure compound | 9 | Menaupause; 12F; Age=50-75Y; BMI=20-35 kg/m² | 50 mg | multiple | 4 weeks | Publications | |||||||||
| 7-Hydroxymatairesinol | 7-Hydroxymatairesinol | Human | Plasma | Unchanged | Capsule of HMR lignan 70% 7-HMR | Pure compound | 9 | Menaupause; 12F; Age=50-75Y; BMI=20-35 kg/m² | 50 mg | multiple | 8 weeks | Publications |