Intervention Studies for the metabolite Secoisolariciresinol with food phytochemical Secoisolariciresinol
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Secoisolariciresinol | Secoisolariciresinol | Human | Urine | Unchanged | Raw flaxseed (2.93 µmol SDG/g) | Food | 9 | Healthy premenopausal; 9F; Age=20-40Y | 5 g/day | multiple | 7 days | 0.22±0,103 ± (SEM) (µmol/24h) | Publications | ||||||||
| Secoisolariciresinol | Secoisolariciresinol | Human | Urine | Unchanged | Raw flaxseed (2.93 µmol SDG/g) | Food | 9 | Healthy premenopausal; 9F; Age=20-40Y | 15 g/day | multiple | 7 days | 0.87±0,31 ± (SEM) (0.31µmol/24h) | Publications | ||||||||
| Secoisolariciresinol | Secoisolariciresinol | Human | Urine | Unchanged | Raw flaxseed (2.93 µmol SDG/g) | Food | 9 | Healthy premenopausal; 9F; Age=20-40Y | 25 g/day | multiple | 7 days | 1.95±0,834 ± (SEM) (µmol/24h) | Publications | ||||||||
| Secoisolariciresinol | Secoisolariciresinol | Human | Urine | Unchanged | Muffin with 25 g flaxseed | Food | 9 | Healthy premenopausal; 9F; Age=20-40Y | 25 g/day | multiple | 7 days | 2.50±0,96 ± (SEM) (µmol/24h) | Publications | ||||||||
| Secoisolariciresinol | Secoisolariciresinol | Human | Urine | Unchanged | Bread with 25 g flaxseed | Food | 9 | Healthy premenopausal; 9F; Age=20-40Y | 25 g/day | multiple | 7 days | 2.52±1,21 ± (SEM) (µmol/24h) | Publications |