Intervention Studies for the metabolite Enterolactone with food phytochemical Flaxseed Secoiridoids
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Flaxseed Secoiridoids | Enterolactone | Human | Plasma | Gut microbiota metabolite | Raw flaxseed (2.93 µmol SDG/g) | Food | 9 | Healthy premenopausal; 9F; Age=20-40Y | 25 g/day | single | 1 days | 24 | 19,65±6,54 (SEM) | 10.86±3,95 ± (SEM) (µmol/24h) | Publications | ||||||
| Flaxseed Secoiridoids | Enterolactone | Human | Plasma | Gut microbiota metabolite | Raw flaxseed (2.93 µmol SDG/g) | Food | 9 | Healthy premenopausal; 9F; Age=20-40Y | 25 g/day | multiple | 8 days | 24 | 25,84±10,92 (SEM) | 10.86±3,95 ± (SEM) (µmol/24h) | Publications | ||||||
| Flaxseed Secoiridoids | Enterolactone | Human | Urine | Gut microbiota metabolite | Raw flaxseed (2.93 µmol SDG/g) | Food | 9 | Healthy premenopausal; 9F; Age=20-40Y | 5 g/day | multiple | 7 days | 1.81±1,09 ± (SEM) (µmol/24h) | Publications | ||||||||
| Flaxseed Secoiridoids | Enterolactone | Human | Urine | Gut microbiota metabolite | Raw flaxseed (2.93 µmol SDG/g) | Food | 9 | Healthy premenopausal; 9F; Age=20-40Y | 15 g/day | multiple | 7 days | 7.28±1,93 ± (SEM) (µmol/24h) | Publications | ||||||||
| Flaxseed Secoiridoids | Enterolactone | Human | Urine | Gut microbiota metabolite | Muffin with 25 g flaxseed | Food | 9 | Healthy premenopausal; 9F; Age=20-40Y | 25 g/day | multiple | 7 days | 13.45±6,42 ± (SEM) (µmol/24h) | Publications | ||||||||
| Flaxseed Secoiridoids | Enterolactone | Human | Urine | Gut microbiota metabolite | Bread with 25 g flaxseed | Food | 9 | Healthy premenopausal; 9F; Age=20-40Y | 25 g/day | multiple | 7 days | 9.77±3,21 ± (SEM) (µmol/24h) | Publications | ||||||||
| Flaxseed Secoiridoids | Enterolactone | Human | Urine | Gut microbiota metabolite | 5g of ground flaxseed a day (10mg SECO/day) | Food | 32 | Postmenopausal;non-smoker;32 W; Age= 66.9 ± 8.2 years, weight: 64.6 ± 12.2 kg; BMI: 24.7 ± 4.1 kg/m² | 5 g/day | Single | 7 weeks periods (cross-over study) | 24.663 nmol (0-24h) | Publications | ||||||||
| Flaxseed Secoiridoids | Enterolactone | Human | Urine | Gut microbiota metabolite | 10g of ground flaxseed a day (20mg SECO/day) | Food | 32 | Postmenopausal;non-smoker;32 W; Age= 66.9 ± 8.2 years, weight: 64.6 ± 12.2 kg; BMI: 24.7 ± 4.1 kg/m² | 10 g/day | Single | 7 weeks periods (cross-over study) | 56.247 nmol (0-24h) | Publications |