Intervention Studies for the metabolite Hydroxytyrosol glucuronide with food phytochemical Hydroxytyrosol
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hydroxytyrosol | Hydroxytyrosol glucuronide | Human | Plasma; Urine | Host metabolism | Capsule containing 250 mg of the olive leaf extract | Extract | 8 | Premenopausal women | 24 h | 0,62±0,23 (SD) | 2,18±0,65 (SD) | 4,76 | 6,53±4,29 (SD) | 2,23 | 8.7e-06-4.5e-05 ng/mL (0-24h) | Publications | |||||
| Hydroxytyrosol | Hydroxytyrosol glucuronide | Human | Plasma; Urine | Host metabolism | Capsule containing 250 mg of the olive leaf extract | Extract | 8 | Postmenopausal women | 24 h | 0,56±0,18 (SD) | 3,27±0,55 (SD) | 6,05 | 6,52±2,65 (SD) | 2,23 | 8.7e-06-4.5e-05 ng/mL (0-24h) | Publications |