Intervention Studies for the metabolite 4'-Hydroxyphenylacetic acid with food phytochemical Hydroxytyrosol
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hydroxytyrosol | 4'-Hydroxyphenylacetic acid | Human | Plasma | Gut microbiota metabolite | 30 mL of virgin olive oil | Food | 13 | Healthy; 7M; 6W | 0,0111 mg | Single | 6 h | 4.95±2,63 (SD) | 439 | (0-5h) | Publications | ||||||
| Hydroxytyrosol | 4'-Hydroxyphenylacetic acid | Human | Plasma | Gut microbiota metabolite | 30 mL of extra virgin olive oil (rich in polyphenols) | Food | 13 | Healthy; 7M; 6W | 0,1992 mg | Single | 6 h | 5.79±2,67 (SD) | 471 | (0-5h) | Publications |