Intervention Studies for the metabolite Homovanillic alcohol sulfate with food phytochemical Virgin olive oil Secoiridoids
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Virgin olive oil Secoiridoids | Homovanillic alcohol sulfate | Human | Urine | Gut microbiota metabolite | 25 mL/day (3 weeks) of a functional low phenol-enriched virgin olive oil | Food | 33 | Hypercholesterolemic (total cholesterol > 200 mg/dL); 19M; 14W | 0.31 mg | Multiple | 21 days | Publications | |||||||||
| Virgin olive oil Secoiridoids | Homovanillic alcohol sulfate | Human | Urine | Gut microbiota metabolite | 25 mL/day (3 weeks) of a functional medium phenol-enriched virgin olive oil | Food | 33 | Hypercholesterolemic (total cholesterol > 200 mg/dL); 19M; 14W | 8.49 mg | Multiple | 21 days | 1.49 µmol (0-24hh) | Publications | ||||||||
| Virgin olive oil Secoiridoids | Homovanillic alcohol sulfate | Human | Urine | Gut microbiota metabolite | 25 mL/day (3 weeks) of a functional virgin olive oil enriched with its own phenolic compounds and with phenolic compounds from thyme | Food | 33 | Hypercholesterolemic (total cholesterol > 200 mg/dL); 19M; 14W | 4.36 mg | Multiple | 21 days | 0.9 to (at24h) | Publications |