Intervention Studies for the metabolite 7-methylxanthine with food phytochemical Caffeine

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	Food Phytochemical		Metabolite	Species	Biofluids	Origin	Dietary Source Description	Dietary Source Classification	Total Number of Subjects	Description of Population	Ingested Amount	Single/Multiple Dose	Duration of the Study	Tmax (h)	Cmax (nM)	AUC (nM/h)	Time covered by AUC (h)	t 1/2 (h)	% of 24h Urinary Excretion	Excreted Amount & Time Interval	Publications

	Food Phytochemical		Metabolite	Species	Biofluids	Origin	Dietary Source Description	Dietary Source Classification	Total Number of Subjects	Description of Population	Ingested Amount	Single/Multiple Dose	Duration of the Study	Tmax (h)	Cmax (nM)	AUC (nM/h)	Time covered by AUC (h)	t 1/2 (h)	% of 24h Urinary Excretion	Excreted Amount & Time Interval	Publications
	Caffeine		7-methylxanthine	Human	Urine	Host metabolism	gelatin capsules with water	pure compound	107	Healthy; 52 M; 55 F; Age= 22 ± 3 y; Spanish	300 mg	Single							3,11±0,21 (SEM)		Publications
	Caffeine		7-methylxanthine	Human	Urine	Host metabolism	dissolved in 200 mL water	pure compound	5	Healthy; Age= 69.6±2.3 y; caucasians	0,005 g/Kg bw	Single							2,32±1,18 (SD)		Publications
	Caffeine		7-methylxanthine	Human	Urine	Host metabolism	70 mL of acqueous solution	pure compound	4	Healthy;M; Age= 26-36 y	350 mg	Single							6,90±1,3 (SEM)		Publications
	Caffeine		7-methylxanthine	Human	Urine	Host metabolism	dissolved in water	pure compound	59	Healthy; 35 M; 33 F; Age= 26.6 y ; 42 Caucasians; 26 Oriental	300 mg	Single							2,50±1,4 (SD)		Publications
	Caffeine		7-methylxanthine	Human	Urine	Host metabolism	dissolved in 200 mL water	pure compound	7	Healthy; age 22.2±4.0 y; caucasians	0,005 g/Kg bw	Single							2,40±1,45 (SD)		Publications
	Caffeine		7-methylxanthine	Human	Urine	Host metabolism	tablets	pure compound	8	Healthy; M; Age= 27 y	200 mg	Single							6,10		Publications

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