Intervention Studies for the metabolite 1,3-dimethyluric acid with food phytochemical Caffeine
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications |
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Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caffeine | 1,3-dimethyluric acid | Human | Plasma | Host metabolism | 350 mL of coffee beverage | food | 13 | Healthy; 6 F (Age = 24–28 y); 7 M (Age= 27–30 y) | 224 mg | Single | 8,00 | 0,151±0,075 (SD) | Publications | ||||||||
| Caffeine | 1,3-dimethyluric acid | Human | Plasma | Host metabolism | 350 mL of coffee beverage | food | 13 | Healthy; 6 F (Age = 24–28 y); 7 M (Age= 27–30 y) | 224 mg | Single | 8,00 | 0,059±0,054 (SD) | Publications | ||||||||
| Caffeine | 1,3-dimethyluric acid | Human | Urine | Host metabolism | gelatin capsules with water | pure compound | 107 | Healthy; 52 M; 55 F; Age= 22 ± 3 y; Spanish | 300 mg | Single | 1,31±0,04 (SEM) | Publications | |||||||||
| Caffeine | 1,3-dimethyluric acid | Human | Urine | Host metabolism | 70 mL of acqueous solution | pure compound | 4 | Healthy;M; Age= 26-36 y | 350 mg | Single | 2,90±0,2 (SEM) | Publications | |||||||||
| Caffeine | 1,3-dimethyluric acid | Human | Urine | Host metabolism | dissolved in water | pure compound | 68 | Healthy; 35 M; 33 F; Age= 26.6 y ; 42 Caucasians; 26 Oriental | 300 mg | Single | 1,20±0,4 (SD) | Publications | |||||||||
| Caffeine | 1,3-dimethyluric acid | Human | Urine | Host metabolism | dissolved in 200 mL water | pure compound | 7 | Healthy; age 22.2±4.0 y; caucasians | 0,005 g/Kg bw | Single | 2,73±0,86 (SD) | Publications | |||||||||
| Caffeine | 1,3-dimethyluric acid | Human | Urine | Host metabolism | dissolved in 200 mL water | pure compound | 5 | Healthy; Age= 69.6±2.3 y; caucasians | 0,005 g/Kg bw | Single | 3,37±0,89 (SD) | Publications | |||||||||
| Caffeine | 1,3-dimethyluric acid | Human | Urine | Host metabolism | tablets | pure compound | 8 | Healthy; M; Age= 27 y | 200 mg | Single | 1,70 | Publications |